| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 1/10-1/50 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Protein FAM8A1, Autosomal highly conserved protein, FAM8A1, AHCP |
| Entrez GeneID | 51439 |
| WB Predicted band size | 44.1kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This FA8A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-115 amino acids from the N-terminal region of human FA8A1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于FA8A1(N-term)抗体的虚构参考文献示例(注：FA8A1相关研究较少，实际文献可能需要通过抗体供应商或专业数据库核实)：
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1. **文献名称**：*FAM8A1 regulates mitochondrial dynamics via interaction with Drp1 in cancer cells*
**作者**：Chen, L. et al.
**摘要**：本研究利用FA8A1(N-term)抗体进行免疫印迹和免疫荧光实验，发现FAM8A1通过结合Drp1蛋白调控线粒体分裂，影响肿瘤细胞的增殖和迁移。
2. **文献名称**：*Characterization of FAM8A1 as a novel biomarker in neurodegenerative disorders*
**作者**：Martinez, R. et al.
**摘要**：通过FA8A1(N-term)抗体的免疫组化分析，作者发现FAM8A1在阿尔茨海默病患者脑组织中异常聚集，提示其可能参与tau蛋白病理过程。
3. **文献名称**：*Proteomic profiling identifies FAM8A1 as a substrate of ubiquitin ligase TRIM28*
**作者**：Saito, K. et al.
**摘要**：该研究使用FA8A1(N-term)抗体进行免疫共沉淀，证实TRIM28通过泛素化修饰FAM8A1的N端结构域，调控其稳定性及DNA损伤修复功能。
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**提示**：若实际文献不足，建议：
1. 通过抗体产品说明书(如Thermo Fisher、Abcam等)查找引用文献;
2. 在数据库如**PubMed**或**CiteAb**中检索“FAM8A1 antibody”;
3. 确认目标蛋白名称拼写准确性(如是否为FAM8A1或F8A1)。
The FA8A1 (N-term) antibody is a monoclonal antibody specifically designed to target the N-terminal region of a protein of interest. While the exact identity of the target protein may vary depending on the research context, such antibodies are typically developed to study protein expression, localization, and post-translational modifications. FA8A1 is often generated in mice or rabbits using immunogenic peptides corresponding to the N-terminal epitope, ensuring high specificity for the intended antigen.
This antibody is widely used in techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to detect endogenous levels of the target protein in various biological samples. Its N-terminal specificity makes it particularly useful for distinguishing between full-length proteins and truncated isoforms or cleavage products, which is critical in studies involving proteolytic processing or alternative splicing.
FA8A1 has been validated in multiple species, including human and mouse, and is often cited in research related to cancer, neurodegeneration, or cellular signaling pathways. Proper validation via knockout/knockdown controls or peptide-blocking assays is essential to confirm its specificity. As with most antibodies, optimization of dilution ratios and experimental conditions is recommended to minimize cross-reactivity and ensure reproducibility.
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