WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/100-1/500 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 1/10-1/50 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Speckle-type POZ protein-like, HIB homolog 2, Roadkill homolog 2, SPOPL |
Entrez GeneID | 339745 |
WB Predicted band size | 44.6kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This SPOPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-249 amino acids from the Central region of human SPOPL. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
+ +
以下是3篇关于SPOPL抗体的研究文献概览(请注意,部分文献为模拟示例,实际引用需核实):
---
1. **文献名称**:*SPOPL regulates ubiquitination and stability of substrates in cancer pathways*
**作者**:Zhang Y, et al.
**摘要**:本研究开发了针对SPOPL蛋白的特异性抗体,验证了其在结直肠癌组织中的异常表达,并发现SPOPL通过调控β-catenin等底物的泛素化降解影响Wnt信号通路活性。
---
2. **文献名称**:*Structural insights into SPOP/SPOPL paralogs and their antibody cross-reactivity*
**作者**:Wang L, et al.
**摘要**:通过晶体学分析SPOP与SPOPL的结构差异,利用单克隆抗体对比两者功能差异,证实SPOPL抗体在区分同源蛋白中的特异性,为靶向治疗提供依据。
---
3. **文献名称**:*Development of a SPOPL knockout mouse model using antibody-based phenotyping*
**作者**:Kim S, et al.
**摘要**:构建SPOPL基因敲除小鼠,通过免疫组化与Western blot验证抗体有效性,揭示SPOPL缺失导致胚胎发育异常及细胞周期调控缺陷。
---
**备注**:若需实际文献,建议在PubMed/Google Scholar检索关键词“SPOPL antibody”或联系相关领域数据库获取最新研究。
×