Cat: IPD-X41344

Recombinant Human ZSCAN1 Protein (Baculovirus),His & Myc

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关键信息

  • 基因名

    ZSCAN1

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 种属

    Human

  • 表达系统

    Baculovirus

  • 标签

    N- His & C- Myc

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q8NBB4

  • 表达区间

    1-408aa

  • 分子量

    49.2 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

ZSCAN1 (Zinc Finger and SCAN Domain Containing 1) is a transcription factor belonging to the zinc finger protein family, which plays crucial roles in various biological processes, including embryonic development, cell differentiation, and apoptosis. It has gained attention in recent years due to its potential involvement in human diseases, particularly in cancer. Studies have indicated that ZSCAN1 could act as a tumor suppressor, influencing cell growth and survival by regulating gene expression networks associated with malignancies. Additionally, ZSCAN1 has been implicated in immune responses and stem cell regulation, highlighting its multifaceted role in cellular homeostasis. Its unique structure, characterized by multiple zinc finger motifs and a SCAN domain, facilitates binding to specific DNA sequences, thereby modulating transcription. The recombinant protein form of ZSCAN1 allows researchers to investigate its functional properties, binding affinities, and interactions with other proteins in a controlled environment. This research can aid in elucidating the precise mechanisms by which ZSCAN1 influences cellular behavior and may pave the way for novel therapeutic strategies targeting ZSCAN1-related pathways. Understanding the dynamics of ZSCAN1 and its potential as a biomarker or therapeutic target in cancer and other diseases can contribute significantly to advancements in personalized medicine. The ongoing research on ZSCAN1 recombinant proteins is crucial for unraveling the complexities of gene regulation networks and their implications in health and disease. Overall, ZSCAN1 represents a promising focus area for future investigations aimed at exploiting its biological functions for therapeutic benefits.

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