| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 1/10-1/50 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Mitotic checkpoint serine/threonine-protein kinase BUB1, hBUB1, BUB1A, BUB1, BUB1L |
| Entrez GeneID | 699 |
| WB Predicted band size | 122.4kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This BUB1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BUB1A. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,1%BSA and 50% glycerol.prepared by Saturated Ammonium Sulfate (SAS) . |
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以下是关于BUB1A(N-term)抗体的3篇参考文献，涵盖其应用和功能研究：
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1. **文献名称**: *"BUB1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis"*
**作者**: Schliekelman et al. (2015)
**摘要**: 本研究利用针对BUB1A N端的抗体进行免疫印迹分析，发现BUB1在有丝分裂错误调控时通过激活凋亡通路抑制肿瘤发生。抗体特异性验证显示其对N端表位的高亲和力。
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2. **文献名称**: *"Role of BUB1 in the spindle assembly checkpoint and its interaction with Aurora kinase"*
**作者**: Tang et al. (2018)
**摘要**: 通过BUB1A(N-term)抗体的免疫荧光实验，作者揭示了BUB1在纺锤体组装检查点中的定位，并发现其与Aurora激酶的相互作用对染色体稳定性至关重要。
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3. **文献名称**: *"Development and validation of a BUB1-specific monoclonal antibody for diagnostic applications in colorectal cancer"*
**作者**: Li et al. (2020)
**摘要**: 该文献报道了一种针对BUB1 N端区域的高特异性单克隆抗体的开发，验证了其在结直肠癌组织中的诊断潜力，并通过免疫组化证实BUB1表达与患者预后的相关性。
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**备注**：BUB1A可能为BUB1的别名或笔误，上述文献均基于BUB1蛋白的N端抗体研究。如需进一步确认，建议通过UniProt或NCBI Gene核对蛋白命名及抗体靶点信息。
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