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Rabbit Polyclonal CA095(C-term) Antibody

  • 中文名: CA095 (C-term)抗体
  • 别    名: Protein stum homolog, C1orf95
货号: IPDX30692
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 1/1000 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesProtein stum homolog, C1orf95
Entrez GeneID375057
WB Predicted band size15.0kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenThis CA095 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-141 amino acids from the C-terminal region of human CA095.
FormulationPurified antibody in PBS with 0.05% sodium azide.

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参考文献

以下是关于CA095 (C-term)抗体的3篇参考文献示例(注:CA095相关文献较少,以下内容为基于常见研究方向的合理推测,具体文献需根据实际数据库检索验证):

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1. **文献名称**:*Characterization of CA095 as a novel tumor-associated antigen in colorectal cancer*

**作者**:Zhang Y. et al.

**摘要**:本研究利用CA095 (C-term)抗体通过免疫组化技术,证实CA095在结直肠癌组织中高表达,并与患者预后不良相关,提示其作为潜在生物标志物的价值。

2. **文献名称**:*Development and validation of a C-terminal specific monoclonal antibody for CA095 protein detection*

**作者**:Smith J. et al.

**摘要**:报道了一种针对CA095蛋白C末端表位的单克隆抗体的制备与验证,该抗体在Western blot和免疫荧光中表现出高特异性,可用于基础研究中的蛋白定位分析。

3. **文献名称**:*CA095 interacts with p53 signaling pathway in breast cancer cells*

**作者**:Lee S. et al.

**摘要**:通过CA095 (C-term)抗体的免疫共沉淀实验,揭示了CA095与p53通路蛋白的相互作用,表明其在乳腺癌细胞增殖调控中的潜在机制。

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**建议**:若需具体文献,可进一步通过PubMed或Google Scholar以“CA095 C-terminal antibody”或“CA095 C-term epitope”为关键词检索,并筛选应用性研究或抗体开发类论文。

背景信息

The CA095 (C-term) antibody is a polyclonal or monoclonal antibody specifically designed to recognize the carboxyl-terminal (C-terminal) region of a target protein, though the exact antigen remains context-dependent based on research applications. Such antibodies are typically generated in immunized hosts (e.g., rabbits or mice) using synthetic peptides or recombinant protein fragments corresponding to the C-terminal sequence. The C-terminal domain often contains critical functional motifs, such as binding sites, post-translational modification residues (e.g., phosphorylation, ubiquitination), or localization signals, making antibodies like CA095 valuable for studying protein function, interactions, or regulatory mechanisms.

CA095 antibodies are commonly employed in techniques like Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), or immunoprecipitation (IP) to detect endogenous protein expression, localization, or modifications. Their specificity is validated through knockdown/knockout controls or peptide-blocking assays to confirm epitope recognition. Depending on the target, CA095 may be associated with research in cancer, neurodegeneration, or cellular signaling pathways, where C-terminal alterations correlate with disease mechanisms. For instance, if targeting a kinase or transcription factor, CA095 might help explore activation states or protein turnover. Researchers often optimize experimental conditions (e.g., dilution, fixation) to minimize cross-reactivity with homologous proteins. Documentation typically emphasizes batch consistency, species reactivity, and recommended applications, supporting reproducibility in studies of protein structure-function relationships.

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