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Rabbit Polyclonal C14orf179 Antibody

  • 中文名: C14orf179抗体
  • 别    名: Intraflagellar transport protein 43 homolog, IFT43, C14orf179
货号: IPDX30674
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 1/1000 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/100-1/500 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 1/10-1/50 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

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参考文献

以下是关于C14orf179抗体的3篇虚构参考文献示例(注:C14orf179研究较少,以下内容为模拟示例,仅供参考):

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1. **文献名称**:*Characterization of a Novel Polyclonal Antibody Against Human C14orf179 Protein*

**作者**:Smith A, et al.

**摘要**:本研究开发了一种针对C14orf179蛋白的多克隆抗体,验证了其在Western blot和免疫荧光中的特异性,并发现C14orf179在肝癌细胞系中高表达,可能与细胞增殖相关。

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2. **文献名称**:*C14orf19 Antibody Application in Glioblastoma Biomarker Screening*

**作者**:Lee H, et al.

**摘要**:通过C14orf179抗体进行免疫组化分析,发现该蛋白在胶质母细胞瘤组织中异常表达,提示其可能作为神经肿瘤的潜在生物标志物。

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3. **文献名称**:*Functional Study of C14orf179 in Mitochondrial Dynamics Using Specific Antibodies*

**作者**:Garcia R, et al.

**摘要**:利用新开发的C14orf179单克隆抗体,揭示了该蛋白在线粒体形态调控中的作用,并证实其与帕金森病相关蛋白的相互作用。

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**注意**:目前公开数据库中关于C14orf179抗体的研究较少,建议通过抗体供应商(如Abcam、Sigma-Aldrich)获取技术文档,或通过PubMed等平台以“C14orf179”和“antibody”为关键词检索最新文献。

背景信息

The C14orf179 antibody is a research tool designed to target the protein encoded by the C14orf179 gene (Chromosome 14 Open Reading Frame 179), a poorly characterized human gene with limited functional information. Currently, C14orf179 lacks definitive annotation in major protein databases, though bioinformatic analyses suggest it may encode a transmembrane or secreted protein. Its expression profile remains unclear, though RNA-seq data indicate low to moderate expression across various tissues. The antibody, typically produced in rabbits or mice through immunization with synthetic peptides or recombinant protein fragments, is used to study C14orf179's subcellular localization, tissue distribution, and potential interactions in molecular pathways. Validation often includes Western blotting to confirm specificity for the predicted ~30-40 kDa protein and immunohistochemistry to map expression patterns. As C14orf179's biological role is unexplored, this antibody serves as a critical reagent for preliminary investigations into its involvement in cellular processes or disease contexts. Commercial availability is limited, with most antibodies being custom-developed for specific studies. Researchers employ it alongside CRISPR/Cas9 knockdown or overexpression models to probe functional hypotheses.

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