WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/100-1/500 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 1/10-1/50 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Ubiquitin-associated domain-containing protein 1, UBA domain-containing protein 1, E3 ubiquitin-protein ligase subunit KPC2, Glialblastoma cell differentiation-related protein 1, Kip1 ubiquitination-promoting complex protein 2, UBAC1, GBDR1, KPC2, UBADC1 |
Entrez GeneID | 10422 |
WB Predicted band size | 45.3kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This UBAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-292 amino acids from the C-terminal region of human UBAC1. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是基于UBAC1相关研究的模拟参考文献示例(实际文献需通过学术数据库查询):
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1. **文献名称**:*UBAC1 modulates NF-κB signaling through Lys-63-linked ubiquitination*
**作者**:Chen et al., 2016
**摘要**:研究利用UBAC1特异性抗体进行免疫共沉淀实验,揭示UBAC1通过K63泛素化修饰调控NF-κB通路的分子机制,证实其在炎症反应中的作用。
2. **文献名称**:*Development and characterization of a monoclonal antibody against human UBAC1 for diagnostic applications*
**作者**:Sato et al., 2018
**摘要**:报道一种高特异性抗UBAC1单克隆抗体的开发,验证其在Western blot和免疫组化中的应用,并探讨UBAC1在结直肠癌组织中的表达异常。
3. **文献名称**:*UBAC1 interacts with the 26S proteasome to regulate protein turnover*
**作者**:Garcia-Ruiz et al., 2020
**摘要**:通过抗体介导的蛋白质互作分析,发现UBAC1与26S蛋白酶体亚基结合,调控底物泛素化依赖的降解过程,提示其在蛋白质稳态中的功能。
4. **文献名称**:*UBAC1 deficiency disrupts endoplasmic reticulum-associated degradation (ERAD) pathways*
**作者**:Kim & Park, 2021
**摘要**:利用UBAC1敲除模型及抗体染色技术,证明UBAC1缺失导致内质网应激加剧,影响错误折叠蛋白的清除效率。
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**建议**:如需真实文献,可通过PubMed或Google Scholar检索关键词“UBAC1 antibody”、“UBAC1 function”等,并筛选涉及抗体开发、机制研究或疾病关联的论文。
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