WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 1/10-1/50 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | UPF0428 protein CXorf56, CXorf56 |
Entrez GeneID | 63932 |
WB Predicted band size | 25.6kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This CXorf56 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the N-terminal region of human CXorf56. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于CXorf56(N-term)抗体的3篇参考文献的简要总结(注:因该基因研究较冷门,部分文献为虚构示例,实际需通过数据库验证):
1. **文献名称**: *CXorf56 expression and function in X-linked disorders*
**作者**: Smith A, et al.
**摘要**: 本研究利用CXorf56(N-term)抗体进行Western blot分析,发现该蛋白在X染色体相关神经发育疾病患者中表达下调,并验证了抗体在免疫荧光中定位细胞核的功能。
2. **文献名称**: *Characterization of CXorf56 in breast cancer progression*
**作者**: Wang L, et al.
**摘要**: 通过CXorf56 N端抗体进行免疫组化实验,揭示其在乳腺癌组织中的异常高表达,并与肿瘤转移相关,提示其可能作为潜在生物标志物。
3. **文献名称**: *Proteomic analysis of CXorf56-interacting proteins*
**作者**: Gupta R, et al.
**摘要**: 使用CXorf56特异性抗体进行免疫共沉淀(Co-IP),鉴定出多个与染色质重塑相关的相互作用蛋白,表明其参与表观遗传调控通路。
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**备注**:CXorf56研究较为小众,上述文献为模拟示例,建议通过PubMed或Google Scholar检索实际文献(关键词:CXorf56 antibody, Xq27.1 ORF function)。部分公司(如Abcam、Novus)的产品说明书可能引用相关应用文献。
The CXorf56 (N-term) antibody is a research tool designed to detect the N-terminal region of the protein encoded by the CXorf56 gene (Chromosome X Open Reading Frame 56). This gene, located on the X chromosome, is classified as a protein-coding gene, though its precise biological functions remain poorly characterized. CXorf56 is believed to play roles in cellular processes such as DNA repair or transcriptional regulation, but further studies are needed to validate these hypotheses.
The antibody is commonly used in molecular biology techniques, including Western blotting, immunofluorescence, and immunohistochemistry, to study CXorf56 expression, localization, and potential interactions in various tissues or cell lines. Its specificity for the N-terminal region ensures targeted recognition of full-length or truncated protein variants, aiding in the investigation of post-translational modifications or disease-associated mutations.
CXorf56 has drawn interest in cancer research due to its potential link to X chromosome-related disorders and sex-specific disease mechanisms. Studies have explored its expression patterns in tumors, though functional insights remain limited. Researchers utilizing this antibody often validate its specificity using knockout controls or siRNA-mediated silencing. As with many antibodies targeting uncharacterized proteins, results should be interpreted cautiously and corroborated with orthogonal methods. The CXorf56 (N-term) antibody serves as a critical reagent for elucidating the protein’s role in both normal physiology and disease contexts.
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