| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | TELO2-interacting protein 1 homolog, Protein SMG10, TTI1, KIAA0406, SMG10 |
| Entrez GeneID | 9675 |
| WB Predicted band size | 122.1kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This K0406 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-69 amino acids from the N-terminal region of human K0406. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是基于常见抗体文献结构的模拟示例(请注意，K0406 (N-term) 抗体相关文献可能需要通过专业数据库验证，以下内容为假设性示例)：
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1. **文献名称**: *Characterization of a Novel N-terminal Specific Antibody for Protein Kinase K0406 in Cancer Models*
**作者**: Zhang L, et al.
**摘要**: 本研究开发并验证了针对蛋白激酶K0406 N端表位的单克隆抗体(克隆号：K0406-N1)，证实其在免疫印迹(WB)和免疫荧光(IF)中的特异性，并应用于乳腺癌细胞系中K0406的亚定位研究，发现其与肿瘤迁移相关信号通路的关联。
2. **文献名称**: *K0406 N-terminal Antibody Application in Neurodegenerative Disease Proteomics*
**作者**: Müller S, et al.
**摘要**: 文章利用K0406 (N-term)抗体对阿尔茨海默病脑组织样本进行蛋白质组学分析，发现K0406的N端片段异常聚集现象，提示其可能与tau蛋白病理沉积存在相互作用。
3. **文献名称**: *Development and Validation of a K0406-N-term Polyclonal Antibody for Plant Stress Response Studies*
**作者**: Gupta R, et al.
**摘要**: 报道了一种针对植物逆境响应蛋白K0406 N端的多克隆抗体制备流程，通过ELISA和免疫组化验证其在拟南芥盐胁迫模型中的表达上调，为植物抗逆机制研究提供工具。
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**说明**：
- 实际文献需通过 **PubMed、Google Scholar** 或抗体供应商官网(如Abcam/CST的"Cite This Product"板块)以抗体编号“K0406”及“N-terminal”为关键词检索。
- 若为小众抗体，建议直接联系生产商获取引用文献列表。
The K0406 (N-term) antibody is a polyclonal antibody generated against a synthetic peptide corresponding to the N-terminal region of a target protein. Produced in rabbit, it is commonly used in immunological assays such as Western blot (WB), immunofluorescence (IF), and immunohistochemistry (IHC) to detect the endogenous expression of the protein. The N-terminal epitope specificity ensures recognition of full-length or specific isoforms, aiding in studies of protein expression, localization, and post-translational modifications.
This antibody is particularly valuable in research focusing on cellular signaling, protein-protein interactions, or disease mechanisms where the target protein plays a role. For instance, it may be applied in cancer biology, neuroscience, or metabolic studies. Validation typically includes specificity confirmation via knockout/knockdown controls or recombinant protein overexpression, ensuring minimal cross-reactivity. Its reactivity is often verified across human, mouse, or rat samples, depending on sequence conservation.
Commercial suppliers provide detailed protocols and validation data, emphasizing batch-to-batch consistency. Researchers prioritize this antibody for its ability to distinguish between splice variants or cleavage products, making it a critical tool in functional proteomics and molecular pathology investigations. Proper storage and optimized dilution ratios are essential for maintaining performance.
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