| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/500 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 1/10-1/50 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Cell cycle control protein 50B, P4-ATPase flippase complex beta subunit TMEM30B, Transmembrane protein 30B, TMEM30B, CDC50B |
| Entrez GeneID | 161291 |
| WB Predicted band size | 38.9kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This CC50B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-71 amino acids from the N-terminal region of human CC50B. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是基于模拟检索列出的3篇可能与CC50B (N-term)抗体相关的参考文献，供参考：
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1. **文献名称**: *Characterization of a Novel N-terminal Antibody for CC50B in Cell Cycle Regulation*
**作者**: Smith J, et al.
**摘要**: 本研究开发了一种特异性识别CC50B蛋白N端表位的单克隆抗体，验证了其在免疫印迹和免疫荧光中的应用。研究发现CC50B通过与CDK2相互作用调控G1/S期转换，抗体阻断实验表明其功能缺失导致细胞周期停滞。
2. **文献名称**: *CC50B as a Potential Biomarker in Breast Cancer: Insights from Immunohistochemical Analysis*
**作者**: Lee H, et al.
**摘要**: 利用CC50B (N-term)抗体对乳腺癌组织样本进行检测，发现CC50B在转移性肿瘤中高表达，且与患者预后不良相关。研究提示其可能成为治疗靶点或诊断标志物。
3. **文献名称**: *Development and Validation of CC50B-Specific Antibodies for Neuronal Localization Studies*
**作者**: Garcia R, et al.
**摘要**: 文章详细描述了兔源多克隆CC50B (N-term)抗体的制备流程，并通过敲除细胞系验证其特异性。该抗体成功应用于大鼠脑组织的免疫组化，显示CC50B在海马神经元突触前膜富集。
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**注意**：以上文献为模拟示例，实际引用需通过学术数据库(如PubMed、Google Scholar)以关键词“CC50B antibody N-terminal”或抗体编号(如产品目录号)检索真实文献。若检索结果有限，建议联系抗体供应商获取技术手册中引用的研究。
The CC50B (N-term) antibody is a monoclonal antibody specifically designed to target the N-terminal region of a protein of interest, often utilized in various research applications such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). While the exact target protein may vary depending on the specific context, antibodies labeled with "CC50B" typically indicate a clone identifier, suggesting its use in detecting cell cycle-related proteins or signaling molecules involved in proliferation, apoptosis, or differentiation. The N-terminal epitope recognition ensures specificity, minimizing cross-reactivity with other protein domains or isoforms.
Developed in host species like rabbit or mouse, CC50B antibodies are often validated for reactivity in human, mouse, or rat samples, supporting studies in cancer biology, developmental biology, or molecular pathways. Their application in research has contributed to understanding protein localization, expression levels, and post-translational modifications under experimental or pathological conditions. As with many research antibodies, proper validation using knockout controls or peptide blocking assays is critical to confirm specificity. CC50B (N-term) remains a tool for elucidating protein function and dynamics in cellular mechanisms, though detailed characterization of its target is essential for accurate experimental interpretation.
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