| WB | 1/1000 | Human, Hamster |
| IF | 咨询技术 | Human, Hamster |
| IHC | 1/100-1/500 | Human, Hamster |
| ICC | 技术咨询 | Human, Hamster |
| FCM | 咨询技术 | Human, Hamster |
| Elisa | 咨询技术 | Human, Hamster |
| Aliases | Zinc finger CCHC domain-containing protein 24, ZCCHC24, C10orf56 |
| Entrez GeneID | 219654 |
| WB Predicted band size | 27.0kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Hamster |
| Immunogen | This ZCH24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-165 amino acids from the C-terminal region of human ZCH24. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于ZCH24 (C-term)抗体的虚构参考文献示例(仅供格式参考，实际文献需查询数据库)：
1. **"Characterization of ZCH24 C-terminal antibody in neuronal protein analysis"**
*作者：Smith A, et al. (2022)*
**摘要**：本研究验证了ZCH24 (C-term)抗体在检测人脑组织中ZCH24蛋白C端结构域的特异性，证实其适用于免疫印迹和免疫组化，并发现其在阿尔茨海默病模型中的表达下调。
2. **"ZCH24 interacts with microtubule-associated proteins: Insights from C-terminal epitope tagging"**
*作者：Lee J, et al. (2020)*
**摘要**：通过ZCH24 (C-term)抗体，作者发现ZCH24蛋白C端与微管结合蛋白Tau存在相互作用，提示其在细胞骨架调控中的潜在作用，研究基于HEK293细胞系和共聚焦显微镜分析。
3. **"Development and validation of a ZCH24 C-terminal-specific monoclonal antibody for cancer biomarker studies"**
*作者：Chen R, et al. (2019)*
**摘要**：报道了一种高灵敏度的ZCH24 (C-term)单克隆抗体的开发，该抗体在结直肠癌组织样本中显示出高特异性，可用于ELISA和流式细胞术，提示ZCH24作为肿瘤标志物的潜力。
4. **"ZCH24 C-terminal phosphorylation and its role in oxidative stress response"**
*作者：Gomez P, et al. (2021)*
**摘要**：利用ZCH24 (C-term)抗体，研究发现ZCH24蛋白C端在氧化应激条件下发生磷酸化修饰，此修饰可能调控其与抗氧化酶GPX4的结合，影响细胞存活。
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**注**：以上内容为模拟生成，实际文献需通过PubMed、Web of Science等平台检索“ZCH24 antibody”或相关关键词获取。若涉及真实研究，请核实抗体编号(如“ZCH24”是否为正确名称)及目标蛋白背景。
The ZCH24 (C-term) antibody is a polyclonal or monoclonal antibody specifically designed to target the C-terminal region of a protein of interest, often denoted as ZCH24 or its associated gene product. The C-terminal domain of proteins is frequently critical for functional activity, protein-protein interactions, or subcellular localization, making antibodies against this region valuable tools for studying protein behavior. ZCH24 antibodies are typically produced in hosts such as rabbits or mice using immunogenic peptides derived from the conserved C-terminal sequence of the target protein.
These antibodies are widely utilized in techniques like Western blotting (WB), immunohistochemistry (IHC), immunofluorescence (IF), and immunoprecipitation (IP) to detect and quantify endogenous levels of the protein in various biological samples. The specificity of ZCH24 (C-term) antibodies is often validated through knockout/knockdown controls or peptide blocking assays to confirm minimal cross-reactivity.
While the exact biological role of the ZCH24 protein may vary depending on the species and context, such antibodies are commonly employed in research focused on cellular signaling, disease mechanisms (e.g., cancer, neurodegenerative disorders), or developmental processes. Researchers rely on ZCH24 (C-term) antibodies to elucidate protein localization, post-translational modifications, or interactions, contributing to broader insights into molecular pathways and therapeutic targets. Proper storage and optimized dilution protocols are essential to maintain antibody efficacy.
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