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Rabbit Polyclonal CP054(C-term) Antibody

  • 中文名: CP054 (C-term)抗体
  • 别    名: Transmembrane protein C16orf54, C16orf54
货号: IPDX30562
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 1/1000 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 1/10-1/50 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesTransmembrane protein C16orf54, C16orf54
Entrez GeneID283897
WB Predicted band size24.4kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenThis CP054 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-198 amino acids from the C-terminal region of human CP054.
FormulationPurified antibody in PBS with 0.05% sodium azide.

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参考文献

以下是3篇与CP054(C-term)抗体相关的文献示例(注:CP054可能为某特定蛋白编号,文献内容为模拟示例):

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1. **文献名称**:*Characterization of CP054 C-terminal domain in cell cycle regulation*

**作者**:Li et al. (2020)

**摘要**:本研究利用CP054 C-term抗体通过免疫沉淀和Western blot分析,证实CP054的C末端结构域与细胞周期蛋白Cyclin D1存在相互作用,可能参与肿瘤细胞增殖调控。

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2. **文献名称**:*Development of a polyclonal antibody targeting CP054 C-terminus for neurodegenerative disease studies*

**作者**:Smith & García (2018)

**摘要**:作者开发了一种针对CP054 C端表位的兔多克隆抗体,验证其在人脑组织切片中的特异性免疫组化染色能力,并发现CP054在阿尔茨海默病模型中的异常聚集。

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3. **文献名称**:*CP054 C-terminal phosphorylation modulates its nuclear localization*

**作者**:Wang et al. (2021)

**摘要**:通过CP054 C-term抗体的免疫荧光实验,揭示了该蛋白C末端的磷酸化修饰对其核质穿梭的关键作用,为DNA损伤修复机制提供了新见解。

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注:若CP054为特定蛋白(如细菌蛋白、非模式生物蛋白等),建议补充更多背景信息以精准检索文献。实际文献需通过PubMed或Google Scholar搜索关键词(如“CP054 antibody C-terminal”)获取。

背景信息

The CP054 (C-term) antibody is a polyclonal or monoclonal antibody specifically designed to recognize the carboxyl-terminal (C-terminal) region of a target protein, often denoted in research by its catalog identifier (e.g., CP054). Such antibodies are typically generated by immunizing host animals (e.g., rabbits, mice) with a synthetic peptide or recombinant protein corresponding to the C-terminal sequence of the protein of interest. The C-terminal region is frequently selected for antibody development due to its unique structural or functional properties, such as containing post-translational modification sites, protein-protein interaction domains, or regulatory motifs critical for the protein's activity.

CP054 (C-term) antibodies are commonly used in techniques like Western blotting (WB), immunohistochemistry (IHC), immunofluorescence (IF), or immunoprecipitation (IP) to study the expression, localization, or interactions of the target protein in cells or tissues. Their specificity for the C-terminus ensures detection of full-length proteins or specific isoforms, avoiding cross-reactivity with truncated variants or unrelated proteins. Validation data, including knockout/knockdown controls or peptide competition assays, are essential to confirm specificity.

These antibodies are valuable tools in research areas such as cellular signaling, cancer biology, or neurodegenerative diseases, where understanding protein dynamics or regulation is critical. Researchers should verify species reactivity (e.g., human, mouse, rat) and application compatibility when using CP054 (C-term) antibodies in experimental workflows.

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