| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 1/10-1/50 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Ribosome biogenesis regulatory protein homolog, RRS1, KIAA0112, RRR |
| Entrez GeneID | 23212 |
| WB Predicted band size | 41.2kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This RRS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human RRS1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于RRS1抗体的3篇代表性文献的简要信息(内容为示例，请以实际文献为准)：
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1. **文献名称**：*RRS1-Mediated Immune Responses in Arabidopsis Require Direct Interaction with RPS4*
**作者**：Williams SJ, et al.
**摘要**：研究揭示了拟南芥抗病蛋白RRS1通过C端WRKY结构域与RPS4蛋白互作，调控病原体免疫反应。文中通过制备RRS1特异性抗体验证其蛋白稳定性，并证明RRS1-RPS4复合物在激活免疫信号中的必要性。
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2. **文献名称**：*The Role of RRS1 in Regulating Plant Cell Death and Disease Resistance*
**作者**：Noutoshi Y, et al.
**摘要**：该研究利用RRS1抗体进行免疫印迹分析，发现RRS1蛋白在病原体侵染后显著积累。实验表明RRS1通过抑制过度的细胞死亡维持抗病平衡，抗体检测为揭示其在信号通路中的动态变化提供关键证据。
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3. **文献名称**：*RRS1 Antibody-Based Screening Identifies Novel Mutants with Enhanced Bacterial Resistance*
**作者**：Li X, et al.
**摘要**：作者开发了高特异性RRS1多克隆抗体，用于筛选拟南芥突变体库，发现RRS1蛋白表达异常的株系对细菌抗性增强，提示其负调控植物免疫的潜在机制。
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**注意**：以上为模拟摘要，实际文献需通过PubMed、Google Scholar等平台检索关键词“RRS1 antibody”或结合具体研究领域(如植物免疫、癌症等)进一步筛选。
The RRS1 (Ribosome-Biogenesis Regulatory Factor Homolog) protein plays a critical role in ribosome assembly, a fundamental process for cellular growth and proliferation. It is conserved across eukaryotes and interacts with components of the 60S ribosomal subunit, facilitating rRNA processing and nuclear export of pre-ribosomal particles. Dysregulation of RRS1 has been linked to pathological conditions, including cancers, where its overexpression correlates with tumor progression, therapy resistance, and poor prognosis, likely due to enhanced ribosome production supporting uncontrolled cell division.
RRS1 antibodies are immunological tools designed to detect and quantify RRS1 protein expression in research settings. These antibodies are typically produced in host organisms (e.g., rabbits, mice) using immunogenic peptide sequences derived from conserved regions of RRS1. They enable techniques like Western blotting, immunofluorescence, and immunohistochemistry to study RRS1 localization, expression dynamics, and interactions in cellular or tissue samples. Validated RRS1 antibodies are essential for investigating its role in diseases, particularly cancer biology, and exploring its potential as a diagnostic or therapeutic target. Recent studies also implicate RRS1 in non-ribosomal functions, such as DNA repair and stress responses, broadening the utility of these antibodies in diverse research contexts.
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