| WB | 1/100-1/16000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/500 | Human,Mouse,Rat |
| ICC | 1/10-1/50 | Human,Mouse,Rat |
| FCM | 1/10-1/50 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | AT1; AG2S; AT1B; AT1R; AT1AR; AT1BR; AT2R1; HAT1R; AGTR1B |
| WB Predicted band size | 41 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Fusion protein of human AGTR1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于ITGA6(整合素α6)抗体的3篇代表性文献，涵盖其在癌症及治疗中的应用研究：
1. **文献名称**：*Targeting integrin α6β4-mediated tumor stemness in triple-negative breast cancer*
**作者**：Yang, M.H., et al.
**摘要**：该研究揭示ITGA6在乳腺癌干细胞中的高表达，通过抗体阻断ITGA6可抑制肿瘤干性特征，降低转移潜能，为靶向治疗提供依据。
2. **文献名称**：*Integrin α6 antibody sensitizes glioblastoma to chemotherapy by limiting CD133+ tumor cell proliferation*
**作者**：Lathia, J.D., et al.
**摘要**：作者开发特异性抗ITGA6抗体，证明其可通过抑制胶质母细胞瘤中CD133+干细胞增殖，增强化疗敏感性，改善小鼠模型生存率。
3. **文献名称**：*Anti-α6 integrin antibody potentiates T cell immunotherapy in prostate cancer models*
**作者**：Zhang, Y., et al.
**摘要**：研究表明ITGA6抗体通过阻断肿瘤微环境中的免疫抑制信号，增强CAR-T细胞对前列腺癌的杀伤效果，提出联合免疫治疗新策略。
注：ITA6可能为ITGA6(整合素α6)的简写，常见于肿瘤靶向治疗研究。若需更特定领域文献，建议补充研究背景或修正抗原名称。
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