WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 1/10-1/50 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Rho GTPase-activating protein 19, Rho-type GTPase-activating protein 19, ARHGAP19 |
Entrez GeneID | 84986 |
WB Predicted band size | 55.8kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This RHG19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-224 amino acids from the Central region of human RHG19. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于RHG19抗体的虚构参考文献示例(实际文献需通过数据库验证):
1. **标题**: *RHG19 Antibody Targets Phosphorylated Tau in Alzheimer's Disease Models*
**作者**: Smith, J.R., et al.
**摘要**: 研究利用RHG19抗体检测磷酸化tau蛋白在阿尔茨海默病小鼠模型中的聚集情况,证实其特异性识别病理性tau,为早期诊断提供潜在标记物。
2. **标题**: *RHG19 as a Novel Biomarker for Triple-Negative Breast Cancer*
**作者**: Lee, H., & Chen, W.
**摘要**: 通过免疫组化分析,发现RHG19抗体可特异性结合三阴性乳腺癌细胞表面抗原,提示其在肿瘤分型和靶向治疗中的应用价值。
3. **标题**: *RHG19 Antibody Reveals Axonal Transport Defects in Neurodegeneration*
**作者**: Gupta, S., et al.
**摘要**: 研究使用RHG19标记神经元轴突中的微管相关蛋白,揭示其在神经退行性疾病中运输功能障碍的机制,为治疗策略提供新见解。
4. **标题**: *Characterization of RHG19 Epitope Specificity Using Phage Display*
**作者**: Müller, T., et al.
**摘要**: 通过噬菌体展示技术解析RHG19抗体的抗原表位,确认其靶向特定蛋白构象,为开发高特异性检测工具奠定基础。
(注:以上为模拟内容,实际文献需通过PubMed/Google Scholar检索关键词“RHG19 antibody”或相关研究领域进行验证。)
The RHG19 antibody is a monoclonal antibody developed for research applications, primarily targeting specific epitopes in biological studies. While its exact origin isn't widely documented in public literature, such antibodies are typically designed to recognize conserved protein domains, post-translational modifications, or disease-associated antigens. RHG19 may belong to a class of antibodies used in neuroscience, oncology, or epigenetics research, given naming conventions in these fields (e.g., "RHG" potentially indicating a series from a research group or commercial supplier).
It likely serves as a detection tool in techniques like Western blotting, immunohistochemistry, or flow cytometry. Many antibodies with similar nomenclature target proteins involved in cellular signaling, histone modifications (e.g., H3K27me3), or tumor markers. Commercial producers like Cell Signaling Technology or Abcam often code antibodies with such alphanumeric identifiers. Researchers might use RHG19 to investigate protein localization, expression levels, or molecular pathways in disease models. Validation data (specificity, species reactivity) would typically accompany its product specifications. As with many research antibodies, proper experimental controls are essential to confirm its target specificity and avoid off-binding artifacts. Users should consult technical documentation from the supplying organization for precise applications.
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