| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/500 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 1/10-1/50 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Phosphatidylcholine:ceramide cholinephosphotransferase 2, Sphingomyelin synthase 2, SGMS2, SMS2 |
| Entrez GeneID | 166929 |
| WB Predicted band size | 42.3kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This SGMS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 338-365 amino acids from the C-terminal region of human SGMS2. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于SGMS2(鞘磷脂合成酶2)抗体的3篇参考文献，按研究领域和内容简要概括：
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1. **文献名称**：*Sphingomyelin synthase 2 deficiency attenuates NFκB activation and osteoclastogenesis in osteoporosis*
**作者**：Li X, et al.
**摘要**：该研究利用SGMS2基因敲除小鼠模型，结合SGMS2特异性抗体检测蛋白表达，发现SGMS2通过调节鞘脂代谢影响NFκB信号通路，进而调控破骨细胞分化和骨质疏松症进程。抗体用于Western blot和免疫组化验证SGMS2在骨组织中的表达变化。
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2. **文献名称**：*SGMS2-mediated sphingomyelin biosynthesis regulates mitochondrial dynamics and neuronal apoptosis*
**作者**：Wang Y, et al.
**摘要**：研究通过SGMS2抗体进行亚细胞定位分析，发现SGMS2在线粒体膜上的富集影响鞘磷脂合成，进一步调控线粒体融合/分裂平衡，并在神经元凋亡中起关键作用。抗体用于免疫荧光和流式细胞术检测SGMS2表达水平与细胞凋亡的关联。
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3. **文献名称**：*A novel mutation in SGMS2 causes rare skeletal dysplasia: Antibody-based diagnostic approach*
**作者**：Smith J, et al.
**摘要**：该研究报道SGMS2基因突变导致罕见骨骼发育异常，通过开发高特异性SGMS2多克隆抗体，对患者成纤维细胞进行蛋白表达定量和功能分析，证明突变导致酶活性丧失及鞘磷脂代谢异常，为疾病诊断提供分子依据。
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**注**：以上文献为示例，实际文献需通过PubMed或Web of Science等平台检索关键词“SGMS2 antibody”或“sphingomyelin synthase 2”获取。若需具体文献DOI或年份信息，可进一步补充关键词筛选。
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