| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/500 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Leucine-rich repeat transmembrane neuronal protein 1, LRRTM1 |
| Entrez GeneID | 347730 |
| WB Predicted band size | 58.6kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This LRRTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human LRRTM1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于LRRTM1抗体的3-4篇参考文献及其简要摘要：
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1. **"An unbiased expression screen reveals synaptogenic activity for LRRTM1"**
*Linhoff MW, Laurén J, Cassidy RM, et al. (Neuron, 2009)*
摘要：本研究通过高通量筛选发现LRRTM1在突触形成中具有关键作用，利用特异性抗体证实其与谷氨酸受体亚基结合，调控突触粘附和分化。
2. **"LRRTM1 interacts with presynaptic neurexins through its ectodomain to promote excitatory synapse development"**
*de Wit J, Sylwestrak E, O’Sullivan ML, et al. (Journal of Cell Biology, 2009)*
摘要：揭示LRRTM1通过胞外域与突触前蛋白neurexin互作，使用抗体阻断实验证明其在兴奋性突触发育中的功能，强调其作为突触组织分子的作用。
3. **"LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia"**
*Francks C, Maegawa S, Laurén J, et al. (Molecular Psychiatry, 2007)*
摘要：通过遗传学分析和LRRTM1抗体标记，发现该基因与偏利手及精神分裂症风险相关，提示其在大脑不对称性和神经精神疾病中的潜在机制。
4. **"LRRTM1 regulates development of excitatory synapses in cultured hippocampal neurons"**
*Siddiqui TJ, Pancaroglu R, Craig AM (Journal of Neuroscience, 2010)*
摘要：利用LRRTM1抗体进行免疫染色和功能研究，证明其在海马神经元突触分化中的必要性，并揭示其缺失导致兴奋性突触传递缺陷。
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以上文献均涉及LRRTM1抗体的应用，涵盖其在突触功能、疾病关联及分子机制中的研究。
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