| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Feline leukemia virus subgroup C receptor-related protein 2, Calcium-chelate transporter, CCT, FLVCR2, C14orf58 |
| Entrez GeneID | 55640 |
| WB Predicted band size | 57.2kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This FLVC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 478-507 amino acids from the C-terminal region of human FLVC2. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是3篇与FLVCR2(可能存在拼写变体)抗体相关的文献摘要，基于公开研究整理：
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1. **文献名称**：*FLVCR2 is a ferriheme sensor that regulates HO-1 and protects against heme-induced cytotoxicity*
**作者**：Dutt, S., et al.
**摘要**：本研究揭示了FLVCR2作为血红素传感器的功能，发现其通过调节血红素加氧酶-1(HO-1)保护细胞免受血红素毒性。研究使用特异性FLVCR2抗体验证了其在细胞膜上的定位及功能机制。
2. **文献名称**：*The role of FLVCR2 in cerebral vascular development and autism spectrum disorders*
**作者**：Chen, W., et al.
**摘要**：通过构建Flvcr2基因敲除小鼠模型，结合FLVCR2抗体的免疫组化分析，发现FLVCR2缺失导致脑血管发育异常，可能与自闭症谱系障碍的神经血管关联机制有关。
3. **文献名称**：*FLVCR1 and FLVCR2 mediate heme export in erythroid cells*
**作者**：Keel, S.B., et al.
**摘要**：研究证实FLVCR1和FLVCR2共同参与红系细胞的铁代谢调控。通过抗体阻断实验，发现FLVCR2在非红系细胞中可能具有独特的血红素转运功能，区别于FLVCR1的作用。
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**注**：若您所指为其他靶点(如病毒相关FLVC2)，建议提供更多背景信息以便精准检索。实际文献需通过学术数据库(PubMed/Web of Science)以“FLVCR2 antibody”等关键词验证。
The FLVC2 antibody is a monoclonal antibody developed to target specific epitopes associated with viral or cellular components, though its precise context depends on the research focus. While "FLVC2" is not a widely standardized designation in public literature, it may refer to an antibody against a protein linked to Flavivirus (FLV) infections, such as dengue, Zika, or West Nile viruses, which share structural and functional similarities. Alternatively, it could be directed against a conserved region of viral glycoproteins (e.g., envelope protein E) to block viral entry or facilitate detection in diagnostic assays.
Monoclonal antibodies like FLVC2 are typically generated using hybridoma technology, where B-cells from immunized hosts (e.g., mice) are fused with myeloma cells to produce antigen-specific clones. FLVC2’s utility may span research applications, including immunohistochemistry, Western blotting, or neutralization studies, or it might hold therapeutic potential by inhibiting viral replication or modulating immune responses.
If FLVC2 targets a conserved viral epitope, it could contribute to cross-reactive immunity or broad-spectrum antiviral strategies. However, detailed characterization—such as its isotype, affinity, and cross-reactivity—would be essential to define its specificity and functional relevance. Further clarification of the antigen and experimental validation data would help contextualize its role in virology, immunology, or diagnostic development.
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