WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/100-1/500 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial, Ubiquinone biosynthesis methyltransferase COQ5, COQ5 |
Entrez GeneID | 84274 |
WB Predicted band size | 37.1kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | This COQ5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-241 amino acids from the Central region of human COQ5. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于COQ5抗体的参考文献示例(注:以下内容为模拟生成,非真实文献):
1. **文献名称**:*COQ5 Methyltransferase Activity in Yeast Mitochondria: Role in Coenzyme Q Biosynthesis*
**作者**:Smith J. et al. (2017)
**摘要**:该研究利用COQ5抗体验证了其在酵母线粒体中的定位,证明COQ5通过甲基化修饰参与辅酶Q(CoQ)的生物合成,并揭示其酶活性对线粒体能量代谢的关键作用。
2. **文献名称**:*COQ5 Expression Correlates with Cancer Cell Metabolism and Prognosis in Colorectal Cancer*
**作者**:Lee H. et al. (2019)
**摘要**:通过免疫组化(使用COQ5特异性抗体)分析结直肠癌组织,发现COQ5高表达与肿瘤细胞线粒体功能异常及患者不良预后显著相关,提示其作为潜在生物标志物的价值。
3. **文献名称**:*A Novel COQ5 Mutation Identified in Patients with Primary CoQ10 Deficiency Syndrome*
**作者**:Garcia R. et al. (2021)
**摘要**:研究报道了一种新型COQ5基因突变导致辅酶Q10缺乏症,利用Western blot(COQ5抗体)证实突变引起蛋白质表达下降,为遗传性线粒体疾病的机制提供了新见解。
4. **文献名称**:*COQ5 as a Therapeutic Target: Insights from Antibody-Based Modulation Studies*
**作者**:Chen L. et al. (2023)
**摘要**:综述了COQ5在疾病中的功能,重点讨论其抗体在靶向治疗开发中的应用潜力,包括抑制辅酶Q合成通路以调控细胞代谢的研究进展。
(注:以上文献信息为示例性质,实际引用请通过学术数据库核实真实文献。)
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