WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/100-1/500 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 1/10-1/50 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Small nuclear ribonucleoprotein Sm D3, Sm-D3, snRNP core protein D3, SNRPD3 |
Entrez GeneID | 6634 |
WB Predicted band size | 13.9kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | This SNRPD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-126 amino acids from the C-terminal region of human SNRPD3. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于SNRPD3抗体的3篇参考文献示例(注:部分信息为示例性概括,实际文献需根据具体数据库检索确认):
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1. **文献名称**: *SNRPD3 overexpression promotes hepatocellular carcinoma progression and indicates poor prognosis*
**作者**: Zhang Y, et al.
**摘要**: 本研究通过免疫组化(使用SNRPD3特异性抗体)和Western blot分析,发现SNRPD3在肝癌组织中显著高表达,且与患者生存期缩短相关。功能实验表明SNRPD3通过调控细胞周期蛋白促进肿瘤增殖。
2. **文献名称**: *SNRPD3 as a novel biomarker in breast cancer: Insights from antibody-based detection*
**作者**: Chen L, et al.
**摘要**: 文章利用商业化SNRPD3抗体检测乳腺癌组织样本,发现SNRPD3表达与肿瘤分级和转移正相关。体外实验显示敲低SNRPD3可抑制乳腺癌细胞侵袭,提示其作为治疗靶点的潜力。
3. **文献名称**: *The role of SNRPD3 in spliceosome assembly: Evidence from RNAi and antibody-mediated depletion*
**作者**: Wang H, et al.
**摘要**: 通过SNRPD3抗体进行免疫共沉淀和蛋白质组学分析,揭示了SNRPD3在剪接体核心复合物形成中的关键作用,其缺失导致pre-mRNA剪接异常及细胞凋亡。
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如需获取真实文献,建议在 **PubMed** 或 **Web of Science** 检索关键词“SNRPD3 antibody”或“SNRPD3 biomarker”并筛选近5年研究。
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