WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 1/10-1/50 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Protein Dos, DOS, C19orf26 |
Entrez GeneID | 255057 |
WB Predicted band size | 73.9kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This C19orf26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 423-450 amino acids from the Central region of human C19orf26. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
+ +
以下是基于假设的关于C19orf26抗体的参考文献示例(注意:以下内容可能包含虚构信息,仅供参考格式):
---
1. **文献名称**: "Characterization of C19orf26 Protein Localization in Mitotic Cells"
**作者**: Smith A, et al.
**摘要**: 本研究通过开发兔源多克隆C19orf26抗体,利用免疫荧光技术揭示了该蛋白在有丝分裂过程中定位于纺锤体极区,提示其可能在细胞分裂调控中发挥作用。
2. **文献名称**: "C19orf26 Expression Profiling in Neurodevelopmental Disorders"
**作者**: Lee J, et al.
**摘要**: 采用Western blot和免疫组化技术,结合特异性C19orf26单克隆抗体,发现该基因在自闭症患者脑组织中的表达显著下调,提示其与神经发育异常相关。
3. **文献名称**: "C19orf26 Antibody Validation for Cancer Biomarker Studies"
**作者**: Garcia R, et al.
**摘要**: 本文验证了一种商业化C19orf26抗体的特异性,并通过质谱分析确认其靶向C19orf26的C端结构域,应用于乳腺癌组织芯片分析显示其高表达与患者预后不良相关。
---
**提示**:实际研究中C19orf26相关文献较少,建议通过以下途径获取准确信息:
1. 在PubMed或Google Scholar检索 **"C19orf26 antibody"** 或 **"C19orf26 protein"**;
2. 查看抗体供应商(如Abcam、Sigma-Aldrich)的产品说明书引用文献;
3. 关注功能基因组学或染色体19开放读码框相关研究。
The C19orf26 antibody is a tool used to detect the protein encoded by the *C19orf26* gene (Chromosome 19 Open Reading Frame 26), a poorly characterized human gene located on chromosome 19. The gene’s exact biological function remains unclear, though studies suggest potential roles in cellular processes such as proliferation, differentiation, or intracellular signaling. C19orf26 is predicted to encode a protein with transmembrane domains, hinting at possible localization in cellular membranes or organelles.
Antibodies targeting C19orf26 are typically developed using recombinant protein fragments or synthetic peptides to ensure specificity. These antibodies are employed in techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to study protein expression, tissue distribution, and subcellular localization. Research has explored C19orf26’s relevance in diseases, including cancer, where altered expression may correlate with tumor progression or metastasis. However, functional studies remain limited, and its mechanistic contributions to pathophysiology are not well-defined.
Validation of C19orf26 antibodies includes testing for cross-reactivity and confirming target specificity via knockout controls. Despite its enigmatic role, the antibody serves as a critical reagent for unraveling C19orf26’s function, aiding in hypothesis-driven studies across molecular biology and translational research. Further work is needed to clarify its interactions and regulatory networks in health and disease.
×