| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/500 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 1/10-1/50 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | CDP-diacylglycerol--inositol 3-phosphatidyltransferase, Phosphatidylinositol synthase, PI synthase, PtdIns synthase, CDIPT, PIS, PIS1 |
| Entrez GeneID | 10423 |
| WB Predicted band size | 23.5kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This CDIPT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-125 amino acids from the Central region of human CDIPT. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是基于CDIPT抗体的研究主题模拟生成的参考文献示例(注：以下为虚构示例，建议通过学术数据库查询真实文献)：
1. **文献名称**: "CDIPT Expression in Colorectal Cancer: Prognostic Implications"
**作者**: Zhang L, et al.
**摘要**: 本研究通过免疫组化及Western blot分析，利用CDIPT抗体检测结直肠癌组织中CDIPT蛋白表达水平，发现其高表达与患者生存期缩短及转移风险增加相关，提示CDIPT可能作为潜在预后标志物。
2. **文献名称**: "Role of CDIPT in Lipid Metabolism Regulation in Hepatocytes"
**作者**: Tanaka K, et al.
**摘要**: 通过siRNA敲低及CDIPT抗体介导的蛋白检测，证实CDIPT通过调控磷脂酰肌醇合成影响肝细胞脂质代谢，为代谢综合征的治疗提供新靶点。
3. **文献名称**: "CDIPT Antibody-Based Detection of Protein Localization in Neuronal Cells"
**作者**: Müller S, et al.
**摘要**: 利用CDIPT抗体的免疫荧光技术，首次揭示CDIPT蛋白在神经元突触前膜的特异性定位，提示其在神经信号传导中的潜在作用。
4. **文献名称**: "CDIPT as a Novel Biomarker in Triple-Negative Breast Cancer"
**作者**: Gupta R, et al.
**摘要**: 通过高通量蛋白质组学筛选结合CDIPT抗体验证，发现CDINK4在三阴性乳腺癌中异常高表达，可能参与肿瘤耐药性调控，为靶向治疗提供依据。
**提示**：以上为模拟内容，实际文献需通过PubMed、Web of Science或Google Scholar检索关键词“CDIPT antibody”、“CDIPT protein function”获取。建议结合研究场景(如癌症、代谢疾病)筛选相关文献。
CDIPT (CDP-diacylglycerol--inositol 3-phosphatidyltransferase) is an enzyme encoded by the CDIPT gene, which plays a critical role in phospholipid biosynthesis. It catalyzes the conversion of CDP-diacylglycerol and inositol to phosphatidylinositol (PI), a fundamental phospholipid in eukaryotic cell membranes. PI and its phosphorylated derivatives (phosphoinositides) are essential for membrane structure, intracellular signaling, vesicle trafficking, and cell growth regulation. Dysregulation of CDIPT has been implicated in various diseases, including cancer and neurological disorders, due to its impact on lipid-mediated signaling pathways.
CDIPT antibodies are immunological tools developed to detect and quantify CDIPT protein expression in research applications. These antibodies are typically produced in host species like rabbits or mice using immunogenic peptides derived from CDIPT’s conserved regions. They are validated for techniques such as Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and flow cytometry. CDIPT antibodies enable the study of PI biosynthesis dynamics, lipid metabolism disorders, and CDIPT’s role in cellular processes like autophagy or apoptosis. Their specificity is often confirmed using knockout controls or siRNA-mediated CDIPT knockdown. As interest in lipidomics and membrane biology grows, CDIPT antibodies remain vital for exploring phospholipid-related mechanisms in health and disease.
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