WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/100-1/500 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | NF-kappa-B-repressing factor, NFkB-repressing factor, Protein ITBA4, Transcription factor NRF, NKRF, ITBA4, NRF |
Entrez GeneID | 55922 |
WB Predicted band size | 77.7kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This NKRF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-233 amino acids from the Central region of human NKRF. |
Formulation | Purified antibody in PBS with 0.05% sodium azide,1%BSA and 50% glycerol.prepared by Saturated Ammonium Sulfate (SAS) . |
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以下是关于NKRF(NF-κB Repressing Factor)抗体的3篇虚构参考文献示例(基于领域知识模拟,非真实文献):
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1. **文献名称**:*NKRF Antibody-Based Detection Reveals Its Role in Suppressing Inflammatory Responses*
**作者**:Smith J, et al.
**摘要**:本研究利用特异性NKRF抗体,通过免疫沉淀和Western blot技术,证实NKRF通过与NF-κB p50亚基结合抑制促炎基因表达。实验表明,NKRF在巨噬细胞中高表达,并在LPS刺激后通过核转位调控炎症反应。
2. **文献名称**:*Development of a Monoclonal Antibody Against NKRF for Tumor Microenvironment Analysis*
**作者**:Lee H, et al.
**摘要**:作者开发了一种高特异性小鼠抗人NKRF单克隆抗体,用于免疫组化分析。研究发现,NKRF在多种实体瘤的间质细胞中高表达,并通过抑制NF-κB通路降低肿瘤细胞的侵袭性,提示其作为癌症治疗靶点的潜力。
3. **文献名称**:*NKRF Antibody Identifies Its Epigenetic Silencing in Autoimmune Disorders*
**作者**:Garcia R, et al.
**摘要**:通过NKRF抗体染色及ChIP-seq分析,发现自身免疫性疾病患者T细胞中NKRF表达显著降低,且其启动子区域呈现高甲基化状态。恢复NKRF表达可缓解NF-κB过度活化,为治疗提供新思路。
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注:以上文献为模拟内容,实际研究中请通过PubMed、Google Scholar等平台检索真实文献。
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