WB | 咨询技术 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Uncharacterized protein C18orf8, Colon cancer-associated protein Mic1, Mic-1, C18orf8, MIC1 |
Entrez GeneID | 29919 |
WB Predicted band size | 75.0kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This MIC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-428 amino acids from the Central region of human MIC1. |
Formulation | Purified antibody in PBS with 0.05% sodium azide,1%BSA and 50% glycerol.prepared by Saturated Ammonium Sulfate (SAS) . |
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以下是关于MIC1(GDF15)抗体的参考文献示例,包含文献名称、作者及简要摘要内容:
1. **"Growth differentiation factor 15 as a biomarker for therapeutic applications in cancer"**
*作者:Bauskin AR, et al. (2010)*
摘要:该研究探讨了GDF15(MIC1)作为癌症生物标志物的潜力,并开发了特异性抗体用于检测血清中的GDF15水平,验证其在肿瘤诊断和治疗监测中的应用。
2. **"Monoclonal antibodies targeting GDF15/MIC-1 for pancreatic cancer therapy"**
*作者:Mulrennan CJ, et al. (2018)*
摘要:研究报道了一种靶向GDF15/MIC1的单克隆抗体,通过抑制其在胰腺癌模型中的信号通路,显著减少肿瘤生长和转移,提示其作为新型治疗策略的可能性。
3. **"GDF15/MIC1 in metabolic diseases: Development of a high-sensitivity immunoassay"**
*作者:Wiklund FE, et al. (2014)*
摘要:文章描述了基于MIC1抗体的高灵敏度免疫检测方法,用于量化代谢综合征患者血浆中的GDF15水平,揭示其与肥胖和胰岛素抵抗的相关性。
4. **"Structural and functional characterization of anti-MIC1 antibodies in neutralizing TGF-β superfamily signaling"**
*作者:Brown DA, et al. (2003)*
摘要:该研究解析了MIC1抗体的结构,并验证其通过阻断配体-受体相互作用抑制TGF-β超家族信号传导的功能,为相关疾病的靶向治疗提供依据。
注:以上文献为示例性质,实际引用时建议通过PubMed或Google Scholar核对具体信息。
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