WB | 咨询技术 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/100-1/500 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Glycerol kinase 2, GK 2, Glycerokinase 2, ATP:glycerol 3-phosphotransferase 2, Glycerol kinase, testis specific 2, GK2, GKP2, GKTA |
Entrez GeneID | 2712 |
WB Predicted band size | 60.6kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | This Glycerol kinase (GPK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-515 amino acids from the C-terminal region of human Glycerol kinase (GPK2). |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于甘油激酶(GK或GPK2)抗体的3篇参考文献及其摘要概述:
1. **文献名称**: "Characterization of a polyclonal antibody against human glycerol kinase 2 (GK2) and its application in tissue expression profiling"
**作者**: Smith A, et al.
**摘要**: 该研究开发了一种针对人源GK2的多克隆抗体,并通过免疫组化和Western blot验证其特异性。研究发现GK2在睾丸和肝脏中高表达,提示其可能在脂质代谢和生殖功能中起重要作用。
2. **文献名称**: "Monoclonal antibody-based detection of mitochondrial glycerol kinase activity in murine models"
**作者**: Brown C, et al.
**摘要**: 作者利用单克隆抗体研究小鼠线粒体GK2的酶活性分布,发现其在能量代谢调节中的关键作用,并验证了该抗体在疾病模型(如糖尿病)中检测GK2表达变化的有效性。
3. **文献名称**: "Role of glycerol kinase 2 in adipocyte differentiation: Insights from antibody-mediated functional inhibition"
**作者**: Lee H, et al.
**摘要**: 通过抗体的功能阻断实验,研究发现GK2在脂肪细胞分化过程中调控甘油代谢通路,其活性缺失导致脂滴形成减少,揭示了GK2在肥胖相关代谢疾病中的潜在机制。
4. **文献名称**: "Development of a high-affinity antibody for diagnosing glycerol kinase deficiency via ELISA"
**作者**: Johnson R, et al.
**摘要**: 该研究报道了一种高灵敏度ELISA检测方法,使用新型GK2抗体对遗传性甘油激酶缺乏症患者进行快速诊断,证实了该抗体在临床检测中的应用潜力。
(注:以上文献为示例性内容,实际文献需通过学术数据库检索确认。)
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