| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/500 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase, Myt1 kinase, PKMYT1, MYT1 |
| Entrez GeneID | 9088 |
| WB Predicted band size | 54.2kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This MYT1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T495 of human MYT1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于 **Phospho-MYT1(T495) 抗体** 的假设参考文献示例(仅供参考，实际文献需根据数据库检索确认)：
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1. **文献名称**：*"PLK1-mediated phosphorylation of MYT1 at Thr495 regulates the G2/M checkpoint in DNA damage response"*
**作者**：Li et al. (2018)
**摘要**：本研究揭示了PLK1激酶通过磷酸化MYT1蛋白的Thr495位点调控G2/M期检查点的机制。作者利用Phospho-MYT1(T495)特异性抗体证明，DNA损伤后该位点的磷酸化水平显著升高，并抑制MYT1的激酶活性，促进细胞周期进程。
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2. **文献名称**：*"Development and validation of a phospho-specific antibody targeting MYT1 at Thr495 for cancer biomarker studies"*
**作者**：Smith et al. (2020)
**摘要**：本文报道了一种针对MYT1蛋白T495磷酸化位点的单克隆抗体的开发与验证。通过免疫印迹和免疫组化实验，证实该抗体在乳腺癌和胶质瘤组织中特异性检测磷酸化MYT1.提示其作为潜在治疗靶点的价值。
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3. **文献名称**：*"Dynamic phosphorylation of MYT1 at Thr495 during oocyte maturation in Xenopus laevis"*
**作者**：Tanaka & Nishiyama (2016)
**摘要**：作者利用Phospho-MYT1(T495)抗体研究非洲爪蟾卵母细胞成熟过程中MYT1的磷酸化动态。结果表明，T495磷酸化水平在减数分裂启动时达到峰值，并与CDK1活性协同调控细胞周期转换。
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4. **文献名称**：*"MYT1 phosphorylation at Thr495 by Aurora-A kinase promotes neuroblastoma cell proliferation"*
**作者**：Chen et al. (2022)
**摘要**：该研究指出，Aurora-A激酶通过磷酸化MYT1的T495位点增强其稳定性，从而促进神经母细胞瘤细胞的增殖。使用Phospho-MYT1(T495)抗体的功能实验表明，抑制该位点磷酸化可显著降低肿瘤生长。
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**注意**：以上文献为示例，实际引用时需通过 **PubMed、Web of Science 或 Google Scholar** 检索真实存在的论文，并核对抗体货号(如CST公司的#12345)及具体应用场景。
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