Cat: IPD-X40007

Recombinant Human STX10 Protein ,His & SUMO

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关键信息

  • 基因名

    STX10

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    STX10; SYN10; Syntaxin-10; Syn10

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N- His-SUMO

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    O60499

  • 表达区间

    2-228aa

  • 分子量

    41.7 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

STX10, or Syntaxin 10, is a member of the syntaxin family, which plays a crucial role in the exocytosis process in eukaryotic cells, facilitating the fusion of vesicles with target membranes. This protein is involved in various cellular processes, including neurotransmitter release, hormone secretion, and membrane trafficking. Research has indicated that STX10 may have regulatory functions in synaptic transmission and is implicated in several neurological diseases, making it a potential target for therapeutic interventions. Additionally, its role in immune responses has garnered interest, as STX10 is involved in the trafficking of proteins necessary for cytokine secretion and other immune functions. Given its multifaceted roles in cellular physiology, the study of STX10 and its recombinant forms could provide insights into fundamental biological processes and disease mechanisms. Understanding how STX10 interacts with other proteins in the exocytotic pathway and elucidating its specific functions could advance our knowledge of cellular communication and contribute to the development of new strategies for treating diseases linked to synaptic dysfunction and immune irregularities. Thus, the recombinant expression and functional characterization of STX10 are vital for unraveling its biological significance and exploring its potential as a therapeutic target.

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