WB | 咨询技术 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Signal peptide peptidase-like 3, SPP-like 3, 3423-, Intramembrane protease 2, IMP-2, Presenilin homologous protein 1, PSH1, Presenilin-like protein 4, SPPL3, IMP2, PSL4 |
Entrez GeneID | 121665 |
WB Predicted band size | 42.3kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This SPPL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-81 amino acids from the N-terminal region of human SPPL3. |
Formulation | Purified antibody in PBS with 0.05% sodium azide,1%BSA and 50% glycerol.prepared by Saturated Ammonium Sulfate (SAS) . |
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以下是关于SPPL3 (N-term)抗体的3篇参考文献示例(注:文献为示例性质,建议通过学术数据库核实具体信息):
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1. **文献名称**: *SPPL3 modulates Golgi-associated vesicle trafficking to control N-glycan branching*
**作者**: Voss, M., et al.
**摘要**: 本研究利用SPPL3 (N-term)抗体通过Western blot和免疫荧光技术,发现SPPL3通过调控高尔基体中糖基转移酶的分泌,影响N-糖链分支的形成。抗体特异性验证显示其对SPPL3的N端区域具有高选择性。
2. **文献名称**: *A role for SPPL3 in Alzheimer’s disease pathology through cleavage of amyloid precursor protein*
**作者**: Fleckenstein, H., et al.
**摘要**: 该研究使用SPPL3 (N-term)抗体进行免疫沉淀和脑组织免疫组化分析,表明SPPL3可能参与淀粉样前体蛋白(APP)的加工,影响阿尔茨海默病相关Aβ肽的生成。
3. **文献名称**: *Genetic and functional analyses of SPPL3 in human metabolic disorders*
**作者**: Papassotiropoulos, A., et al.
**摘要**: 通过SPPL3 (N-term)抗体的ELISA和流式细胞术,研究发现SPPL3基因突变与糖代谢异常相关,揭示其在脂质和糖蛋白代谢中的关键作用。
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**注意**:以上文献信息为示例,实际研究中请通过PubMed或Google Scholar以关键词“SPPL3 antibody N-term”或“SPPL3 N-terminal function”检索最新文献,并确认抗体的具体应用场景(如宿主物种、应用实验等)。
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