Cat: IPD-X39965

Recombinant Human RAE1 Protein ,GST

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关键信息

  • 基因名

    RAE1

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    Rae1 protein homolog mRNA-associated protein mrnp 41

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N- GST

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P78406

  • 表达区间

    1-368aa

  • 分子量

    68 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

RAE1 (RNA export 1) is a member of the nucleoporins, proteins that form the nuclear pore complex (NPC) and play crucial roles in nucleocytoplasmic transport. Recent studies have highlighted the importance of RAE1 in various cellular processes, particularly in the export of RNA and proteins from the nucleus to the cytoplasm. It is also implicated in regulating cell proliferation and apoptosis, making it a significant player in cancer biology. Research indicates that RAE1 interacts with other key proteins involved in mRNA transport and may influence gene expression through these interactions. The recombinant expression of RAE1 protein has become a focal point, enabling scientists to dissect its functional mechanisms and explore its potential as a therapeutic target. As RAE1 has been linked to oncogenesis and viral replication, understanding its structure and function opens avenues for developing innovative strategies to tackle cancer and viral infections. Overall, the study of RAE1 recombinant protein not only illuminates fundamental aspects of cell biology but also holds promise for advancements in biomedical research.

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