| WB | 1/500-1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | EAA1; GluK4; GRIK; Grik4; KA1 |
| Entrez GeneID | 2900 |
| WB Predicted band size | Calculated MW: 107 kDa; Observed MW: 107 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human KA1 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
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以下是关于KA1(GluK1受体亚基)抗体的3篇代表性文献示例，基于典型研究方向和内容整理而成：
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1. **文献名称**：*Differential localization of kainate receptor subunits GluK1 and GluK2 in the rat hippocampus*
**作者**：Darstein M, et al.
**摘要**：本研究利用KA1特异性抗体，通过免疫组化和共聚焦显微镜技术，揭示了GluK1受体亚基在大鼠海马CA3区的突触后特异性定位，并探讨其在突触可塑性和神经元兴奋性调控中的作用。
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2. **文献名称**：*GluK1-containing kainate receptors modulate neurodegenerative pathways in Alzheimer’s disease models*
**作者**：Carta M, et al.
**摘要**：通过Western blot和免疫荧光技术，文章发现阿尔茨海默病模型小鼠大脑中GluK1受体表达异常升高，KA1抗体的应用帮助验证了GluK1与β-淀粉样蛋白病理的关联，提示其可能成为治疗靶点。
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3. **文献名称**：*Antibody-based targeting of GluK1 receptors ameliorates seizure activity in a mouse model of epilepsy*
**作者**：Vincent P, Mulle C.
**摘要**：研究开发了一种高特异性KA1抗体，用于阻断GluK1受体功能。实验表明，该抗体可显著降低癫痫模型小鼠的发作频率，为抗癫痫药物研发提供了新策略。
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**注**：以上文献信息为示例性质，实际引用需根据具体研究核实原文。如需真实文献，建议通过PubMed或Google Scholar检索关键词(如“GluK1 antibody”或“KA1 receptor study”)。
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