关键信息
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基因名
CECD
- 应用
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别名
CECDCecropin-D
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种属
Bombyx mori
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O76146
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表达区间
25-60aa
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分子量
7.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
The research background of CECD (C-Terminal Ectodomain of Cadherin) recombinant proteins revolves around their critical role in cell adhesion and signaling processes. Cadherins are a family of transmembrane proteins that mediate cell-cell adhesion in various tissues, playing pivotal roles in development, tissue maintenance, and homeostasis. The ectodomain of cadherins, particularly the C-terminal portion, is essential for the proper functioning of these proteins, influencing their adhesive properties and interactions with intracellular signaling pathways. With advancements in recombinant DNA technology, scientists have been able to produce CECD proteins in vitro, allowing for detailed studies of their structure-function relationships. Research efforts focus on understanding how CECD proteins contribute to cellular behaviors and how they might be exploited in therapeutic applications, such as in cancer treatment, where aberrant cadherin expression often correlates with metastatic potential. Additionally, CECD proteins are being investigated for their potential to serve as biomarkers or targets for drug development, as modulating cadherin-mediated interactions could offer new avenues for intervention in various diseases. This research is crucial for advancing our understanding of cellular mechanics and developing novel strategies for disease management.
