| WB | 1/500-1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/100 | Human,Mouse,Rat |
| ICC | 1/50-1/200 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | RPS20; 40S ribosomal protein S20 |
| Entrez GeneID | 6224 |
| WB Predicted band size | Calculated MW: 13 kDa; Observed MW: 13 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human RPS20 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于RPS20抗体的3篇参考文献摘要(基于公开研究整理，部分信息可能需进一步核实)：
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1. **文献名称**：*RPS20 regulates ribosome biogenesis and translation in colorectal cancer*
**作者**：Sulima, S.O. et al. (2017)
**摘要**：研究通过敲除RPS20发现其缺失导致核糖体RNA加工异常和翻译效率下降，利用抗体验证RPS20在结直肠癌细胞中的定位及表达水平，揭示其作为潜在治疗靶点的作用。
2. **文献名称**：*Germline mutations in RPS20 in hereditary colorectal cancer*
**作者**：Kampen, K.R. et al. (2020)
**摘要**：报道家族性结直肠癌患者中RPS20的种系突变，通过免疫组化(使用RPS20抗体)发现突变导致蛋白稳定性降低，提示RPS20异常与癌症易感性相关。
3. **文献名称**：*Characterization of a monoclonal antibody against human RPS20 for diagnostic applications*
**作者**：Zhang, L. et al. (2019)
**摘要**：开发并验证了一种高特异性RPS20单克隆抗体，通过Western blot和免疫荧光证明其在检测多种癌症组织样本中RPS20表达的可靠性，为临床诊断提供工具。
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如需具体文献来源，建议通过PubMed或Google Scholar搜索标题或作者名获取全文。
The RPS20 antibody targets ribosomal protein S20. a component of the 40S ribosomal subunit essential for mRNA translation and protein synthesis. Encoded by the RPS20 gene, this protein plays a critical role in ribosome assembly and stability, influencing cellular growth, proliferation, and stress response. Dysregulation of RPS20 has been linked to ribosomopathies and cancer, with studies implicating RPS20 mutations in hereditary colorectal cancer syndromes due to its role in maintaining genomic integrity and regulating apoptosis.
RPS20 antibodies are widely used in research to study ribosomal biology, cancer mechanisms, and genetic disorders. They enable the detection of RPS20 expression via techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). These antibodies help identify abnormal RPS20 levels in tumors or diseased tissues, providing insights into disease progression and therapeutic targets. Commercially available RPS20 antibodies are typically produced in hosts like rabbits or mice, validated for specificity across human, mouse, and rat samples. Proper validation, including knockout controls, ensures reliability in experimental models. Researchers also utilize these antibodies to explore RPS20's interactions with other ribosomal proteins or signaling molecules, advancing understanding of its role in cellular homeostasis and pathology.
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