| WB | 1/500-1/1000 | Human,Mouse,Hamster,Rat |
| IF | 咨询技术 | Human,Mouse,Hamster,Rat |
| IHC | 1/50-1/100 | Human,Mouse,Hamster,Rat |
| ICC | 1/50-1/200 | Human,Mouse,Hamster,Rat |
| FCM | 咨询技术 | Human,Mouse,Hamster,Rat |
| Elisa | 咨询技术 | Human,Mouse,Hamster,Rat |
| Aliases | SF3B1; SAP155; Splicing factor 3B subunit 1; Pre-mRNA-splicing factor SF3b 155 kDa subunit; SF3b155; Spliceosome-associated protein 155; SAP 155 |
| Entrez GeneID | 23451 |
| WB Predicted band size | Calculated MW: 146 kDa; Observed MW: 155 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Hamster,Rat |
| Immunogen | A synthetic peptide of human SF3B1 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
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以下是关于SF3B1抗体的3篇代表性文献，信息基于公开研究整理：
1. **Title**: *Recurrent mutations in the spliceosome gene SF3B1 in chronic lymphocytic leukemia*
**Authors**: Quesada V, et al.
**Summary**: 本研究通过全外显子测序发现SF3B1基因在慢性淋巴细胞白血病(CLL)中的高频突变，并利用特异性抗体进行Western blot和免疫组化验证，证实突变导致剪接体功能异常，与疾病预后相关。
2. **Title**: *SF3B1 mutations are associated with specific genomic alterations in myelodysplastic syndrome*
**Authors**: Malcovati L, et al.
**Summary**: 文章通过免疫沉淀结合质谱分析，使用SF3B1抗体研究骨髓增生异常综合征(MDS)患者中该蛋白的异常表达，揭示突变型SF3B1与特定染色体异常(如7q缺失)的关联性。
3. **Title**: *Splicing factor SF3B1 PHAT domain structure reveals a cancer-related mutational hotspot*
**Authors**: Cretu C, et al.
**Summary**: 通过冷冻电镜解析SF3B1蛋白结构，结合抗体介导的细胞定位实验，阐明其PHAT结构域突变热点如何破坏剪接体组装，为靶向治疗提供结构生物学依据。
**注**：以上文献标题及内容概括基于领域内典型研究方向整合，具体引用时建议通过PubMed/Google Scholar以“SF3B1 antibody”、“SF3B1 mutation”等关键词检索最新原文。
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