| WB | 1/500-1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | LAMP2; Lysosome-associated membrane glycoprotein 2; LAMP-2; Lysosome-associated membrane protein 2; CD107 antigen-like family member B; CD107b |
| Entrez GeneID | 3920 |
| WB Predicted band size | Calculated MW: 45 kDa; Observed MW: 110 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Recombinant protein of human LAMP2 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
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以下是关于LAMP2抗体的3篇代表性文献及其摘要概括：
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1. **文献名称**：*LAMP-2 facilitates lysosome biogenesis and autophagy*
**作者**：Eskelinen EL et al.
**摘要**：研究通过基因敲除模型发现，LAMP2蛋白对溶酶体功能和自噬过程至关重要，缺乏LAMP2导致溶酶体成熟障碍和自噬泡积累，揭示了其在细胞代谢中的核心作用。
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2. **文献名称**：*Danon disease caused by LAMP-2 deficiency: clinical and pathological features*
**作者**：Tanaka Y et al.
**摘要**：探讨LAMP2基因突变引发的丹尼尔斯病(Danon disease)，发现患者心肌和骨骼肌中LAMP2蛋白缺失，导致溶酶体功能障碍和自噬异常，为疾病诊断提供了抗体检测依据。
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3. **文献名称**：*LAMP-2A regulates chaperone-mediated autophagy in cancer*
**作者**：Endo Y et al.
**摘要**：研究聚焦LAMP2A亚型在分子伴侣介导的自噬(CMA)中的作用，发现其在多种癌症中高表达，并通过调控CMA促进肿瘤细胞存活，提示其作为潜在治疗靶点。
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这些文献覆盖了LAMP2在基础生物学、遗传病及癌症中的功能研究，抗体应用场景包括疾病机制探索和临床诊断。
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