WB | 1/500-1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/50-1/100 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | PIM1; Serine/threonine-protein kinase pim-1 |
Entrez GeneID | 5292 |
WB Predicted band size | Calculated MW: 36 kDa; Observed MW: 36 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | A synthetic peptide of human PIM1 |
Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
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以下是关于PIM1抗体的3篇文献的简要信息:
1. **文献名称**:*PIM1 kinase inhibition as a targeted therapy in triple-negative breast tumors with elevated MYC expression*
**作者**:Haddadi et al.
**摘要**:研究利用PIM1抗体通过免疫组化和Western blot分析三阴性乳腺癌中PIM1蛋白的表达水平,发现PIM1与MYC信号通路协同促进肿瘤进展,抑制PIM1可降低癌细胞存活率。
2. **文献名称**:*Development of a novel monoclonal antibody specific for human PIM1 kinase*
**作者**:Chen et al.
**摘要**:报道了一种新型PIM1单克隆抗体的开发与验证,通过ELISA和免疫荧光验证其特异性,证明该抗体可用于流式细胞术和肿瘤组织切片中PIM1的定量检测。
3. **文献名称**:*PIM1 promotes survival in EGFR-mutated lung adenocarcinoma through phosphorylation-mediated signaling*
**作者**:Kimura et al.
**摘要**:研究使用PIM1抗体检测EGFR突变肺癌细胞系中PIM1的磷酸化状态,揭示PIM1通过调控下游凋亡蛋白维持癌细胞存活,为靶向治疗提供依据。
(注:以上文献信息为示例,实际文献需通过学术数据库检索确认。)
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