| WB | 1/500-1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | TRAX |
| Entrez GeneID | 7257 |
| WB Predicted band size | Calculated MW: 33 kDa; Observed MW: 33 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthetic peptide of human TRAX |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
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以下是关于Translin Associated Protein X(TRAX)抗体的3篇示例参考文献(内容为虚构，仅供格式参考)：
1. **文献名称**: "TRAX regulates neuronal development via RNA interference pathways"
**作者**: Chen L, et al.
**摘要**: 研究利用TRAX特异性抗体(货号ABX-203)，通过免疫共沉淀和Western blot技术，揭示了TRAX在哺乳动物神经元分化中通过调控microRNA通路影响突触可塑性的分子机制。
2. **文献名称**: "Interaction of TRAX with C3PO complex in gene silencing"
**作者**: Wang Y, et al.
**摘要**: 该文献通过免疫荧光和蛋白质印迹(使用抗TRAX多克隆抗体)，证实TRAX与C3PO复合物结合，在RNA诱导的基因沉默中发挥关键作用，并验证了抗体在HEK293细胞系中的特异性。
3. **文献名称**: "Dysregulation of TRAX in glioblastoma progression"
**作者**: Kim S, et al.
**摘要**: 研究利用商业化TRAX单克隆抗体(克隆号2C8)，分析了脑胶质瘤患者组织中TRAX蛋白表达的下调与肿瘤侵袭性的相关性，提示其作为潜在生物标志物的价值。
*注：以上文献为模拟示例，实际引用请通过PubMed或学术数据库检索真实文献(如PMID: 12345678)。*
The Translin-Associated Protein X (TRAX), also known as C3orf26 or TSNAX, is a highly conserved protein that interacts with Translin to form the Translin-TRAX complex (C3PO). This complex plays critical roles in RNA interference (RNAi) pathways, particularly in processing small RNA molecules like siRNAs and miRNAs. TRAX is implicated in regulating RNA metabolism, genomic stability, and synaptic plasticity, with emerging roles in neurodevelopment and neurodegenerative disorders.
TRAX antibodies are essential tools for studying its expression, localization, and interactions. They enable detection via techniques such as Western blotting, immunohistochemistry, and immunofluorescence. Researchers use these antibodies to explore TRAX's involvement in DNA repair, RNA silencing, and its dysregulation in conditions like schizophrenia, autism spectrum disorders, and glioblastoma. Notably, TRAX's interaction with Translin influences mRNA transport in neurons, linking it to synaptic function and cognitive processes.
Commercial TRAX antibodies are typically raised against specific epitopes (e.g., human TRAX amino acids 1-100) and validated for cross-reactivity in model organisms. Recent studies also highlight TRAX's role in cancer progression, particularly in regulating tumor-suppressive miRNAs. Its dual functions in RNA processing and cellular stress responses make TRAX a compelling target for both basic research and therapeutic development. Antibody specificity is often confirmed using TRAX-knockout cell lines to ensure accurate experimental interpretation.
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