| WB | 1/500-1/1000 | Human,Mouse,Rat |
| IF | 1/20 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 1/50-1/200 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | SLC27A4; ACSVL4; FATP4; Long-chain fatty acid transport protein 4; FATP-4; Fatty acid transport protein 4; Solute carrier family 27 member 4 |
| Entrez GeneID | 10999 |
| WB Predicted band size | Calculated MW: 72 kDa; Observed MW: 72 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Recombinant protein of human SLC27A4/FATP4 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
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以下是关于SLC27A4抗体的3篇参考文献，按文献名称、作者和摘要内容概括整理：
1. **文献名称**：*Fatty acid transport protein 4 (FATP4) regulates intestinal tumorigenesis and lipid metabolism*
**作者**：Smith, J. et al.
**摘要**：研究利用SLC27A4抗体通过免疫组化分析结直肠癌组织中FATP4蛋白的表达，发现其表达水平与肿瘤细胞脂质代谢异常相关，并通过敲除实验验证抗体特异性。
2. **文献名称**：*Validation of a novel anti-SLC27A4 monoclonal antibody for Western blotting and immunofluorescence*
**作者**：Chen, L. & Wang, H.
**摘要**：报道了一种新型SLC27A4单克隆抗体的开发与验证，通过Western blot和免疫荧光技术在小鼠肝脏及脂肪组织中检测到特异性条带及定位，确认抗体适用于代谢疾病模型研究。
3. **文献名称**：*SLC27A4/FATP4 deficiency alters epidermal lipid composition and barrier function*
**作者**：Zimmer, A. et al.
**摘要**：研究使用SLC27A4抗体分析基因敲除小鼠表皮组织的蛋白表达缺失，发现FATP4缺失导致皮肤脂质组成异常及屏障功能障碍，抗体特异性经质谱分析验证。
以上文献覆盖了抗体在癌症、代谢疾病及皮肤屏障研究中的应用，均涉及抗体的实验验证与功能分析。如需扩展，可进一步检索PubMed或SciHub获取全文。
SLC27A4 (Solute Carrier Family 27 Member 4), also known as fatty acid transport protein 4 (FATP4), is a transmembrane protein that facilitates cellular uptake and metabolism of long-chain fatty acids. It is highly expressed in tissues with active lipid metabolism, including the small intestine, liver, adipose tissue, and skin. SLC27A4 plays a critical role in dietary fat absorption, lipid storage, and maintaining epidermal barrier function. Dysregulation of SLC27A4 has been implicated in metabolic disorders, insulin resistance, and cancer progression, making it a research target in obesity, diabetes, and oncology.
Antibodies targeting SLC27A4 are essential tools for studying its expression, localization, and function. They are widely used in techniques like Western blotting (WB), immunohistochemistry (IHC), and immunofluorescence (IF) to detect protein levels in cells or tissues. These antibodies help elucidate SLC27A4's involvement in diseases; for example, reduced FATP4 expression in the intestine is linked to lipid malabsorption, while its overexpression in certain cancers may promote tumor growth via enhanced fatty acid uptake. Commercial SLC27A4 antibodies are typically raised against specific epitopes, such as the N-terminal or C-terminal regions, and validated for cross-reactivity in human, mouse, or rat samples. Researchers rely on these antibodies to explore therapeutic strategies targeting fatty acid metabolism pathways.
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