关键信息
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基因名
Integrin beta-1/CD29
- 应用
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别名
Fibronectin receptor subunit beta VLA-4 subunit beta CD_antigen: CD29
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种属
Mouse
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P09055
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表达区间
21-728aa
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分子量
82.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
Integrin beta-1, also known as CD29, is a crucial component of the integrin family, which plays a significant role in cell adhesion, migration, and communication with the extracellular matrix (ECM). It is a receptor that partners with various alpha subunits to form integrin heterodimers, enabling cells to interact with fibronectin, collagen, and other ECM components. Research on recombinant integrin beta-1/CD29 proteins has gained momentum due to their implications in various biological processes, including wound healing, tumor metastasis, and immune responses. The ability to produce recombinant forms of CD29 has facilitated the study of its structural and functional characteristics, allowing researchers to investigate its role in disease mechanisms and its potential as a therapeutic target. Understanding the interactions and signaling pathways mediated by integrin beta-1/CD29 can pave the way for novel treatments for conditions such as cancer, fibrosis, and autoimmune diseases. Through advances in recombinant protein technology, scientists aim to elucidate the complex roles of integrin beta-1/CD29 in both normal physiology and pathological conditions, highlighting its significance in biomedical research.
