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Rabbit Monoclonal MTX3 Antibody

  • 中文名： MTX3抗体
  • 别    名： Metaxin-3
货号: IPDX21695
Price： ￥1280
数量：
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验证与应用

应用及物种
WB 1/500-1/1000 Mouse,Rat
IF 咨询技术 Mouse,Rat
IHC 咨询技术 Mouse,Rat
ICC 技术咨询 Mouse,Rat
FCM 咨询技术 Mouse,Rat
Elisa 咨询技术 Mouse,Rat

产品详情

AliasesMetaxin-3
Entrez GeneID345778
WB Predicted band sizeCalculated MW: 35 kDa; Observed MW: 35 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityMouse,Rat
ImmunogenA synthetic peptide of human MTX3
FormulationPurified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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参考文献

以下是关于MTX3抗体的虚构参考文献示例(仅供格式参考，实际文献需通过学术数据库查询)：

1. **标题**：MTX3 Antibody Characterization in Ovarian Cancer Biomarker Discovery

**作者**：Chen L, et al.

**摘要**：本研究利用新型MTX3多克隆抗体，通过免疫组化和Western blot技术，揭示了MTX3蛋白在卵巢癌组织中的高表达，并与患者预后不良显著相关，提示其作为潜在治疗靶点的价值。

2. **标题**：Development of a Monoclonal MTX3 Antibody for Lung Adenocarcinoma Diagnosis

**作者**：Sato K, et al.

**摘要**：团队开发了一种高特异性MTX3单克隆抗体，验证其在肺癌细胞系和患者血清中的敏感性，证实MTX3可作为早期肺癌诊断的血清标志物。

3. **标题**：MTX3 Antibody Application in Neuronal Protein Interaction Studies

**作者**：Müller R, et al.

**摘要**：通过MTX3抗体的免疫共沉淀技术，研究发现MTX3与tau蛋白的相互作用可能参与阿尔茨海默病的病理过程，为神经退行性疾病机制提供新见解。

4. **标题**：MTX3 Autoantibodies as a Novel Indicator in Autoimmune Diseases

**作者**：Garcia M, et al.

**摘要**：首次报道类风湿关节炎患者血清中存在MTX3自身抗体，其滴度与疾病活动度呈正相关，提示其在自身免疫监测中的潜在应用。

**注意**：以上内容为模拟示例，MTX3相关研究需以实际文献为准。建议通过PubMed、Web of Science等平台，以“MTX3 antibody”或“MTX3 protein”为关键词检索最新研究。

背景信息

The MTX3 antibody targets the MTX3 protein (metaxin 3), a mitochondrial outer membrane protein involved in protein import and mitochondrial function. MTX3 is part of the metaxin family, which includes MTX1 and MTX2. and plays a role in the assembly of the mitochondrial protein import complex. It is implicated in maintaining mitochondrial integrity, oxidative phosphorylation, and apoptosis regulation. MTX3 antibodies are primarily used in research to study mitochondrial dynamics, cellular stress responses, and diseases linked to mitochondrial dysfunction, such as neurodegenerative disorders, cancer, and metabolic syndromes. These antibodies enable detection of MTX3 expression via techniques like Western blotting, immunofluorescence, and immunohistochemistry, helping to elucidate its tissue-specific distribution and interaction partners. Recent studies suggest MTX3 may influence cancer progression by modulating mitochondrial metabolism and reactive oxygen species (ROS) levels. However, its precise mechanistic roles remain under investigation. MTX3 antibodies thus serve as critical tools for exploring mitochondrial biology and its implications in pathophysiology, offering potential insights into therapeutic strategies targeting mitochondrial pathways.

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