关键信息
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基因名
ADORA2b
- 应用
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种属
Human
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表达系统
E. coli
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标签
Two N- s, His- & SUMO-
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P29275
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表达区间
Gln260~Leu332
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分子量
19kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
ADORA2b, a subtype of the adenosine receptor family, plays a critical role in various physiological processes, including modulation of inflammation, immune responses, and cardiovascular functions. It is a G protein-coupled receptor (GPCR) that primarily interacts with adenosine, a nucleoside involved in cellular energy transfer and signaling. This receptor's activation has been linked to several pathophysiological conditions, such as cancer progression, chronic inflammatory diseases, and cardiovascular disorders. Research into recombinant ADORA2b protein focuses on understanding its structure, signaling pathways, and functional roles in different biological contexts. By producing ADORA2b in recombinant systems, scientists aim to elucidate its mechanisms of action and potential as a therapeutic target. Additionally, the study of this receptor can facilitate the development of novel drugs that modulate its activity, offering new avenues for treatment in conditions where adenosine signaling is disrupted. Overall, the investigation of ADORA2b recombinant proteins is a pivotal aspect of contemporary biomedical research, aiming to unlock new insights into receptor pharmacology and its implications for human health.
