Cat: IPD-X41053

Recombinant Mouse Arid5a Protein (Yeast),His

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关键信息

  • 基因名

    Arid5a

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    Short name: ARID domain-containing protein 5A

  • 种属

    Mouse

  • 表达系统

    Yeast

  • 标签

    N- His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q3U108

  • 表达区间

    1-590aa

  • 分子量

    65.9 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

Arid5a, a member of the AT-rich interaction domain (ARID) protein family, plays a pivotal role in various biological processes, including cell differentiation, proliferation, and transcription regulation. Recent studies have highlighted its significance in hematopoiesis and immune responses, indicating its potential involvement in the development of hematological malignancies. Given its function as a transcriptional regulator, understanding the molecular mechanisms of Arid5a can provide insights into how dysregulation contributes to disease progression. Additionally, Arid5a's influence on the stability and function of mRNA, particularly in immune cells, underscores its relevance in the context of inflammation and autoimmunity. The recombination and characterization of Arid5a protein are essential for elucidating its biological roles and interactions, offering potential avenues for therapeutic interventions. By exploring the structural and functional properties of Arid5a, researchers aim to identify novel regulatory pathways and develop strategies to target its activity in diseases where it is implicated. The generation of recombinant Arid5a protein is crucial for in vitro studies, allowing scientists to dissect its function and potential as a biomarker or therapeutic target in various pathologies. Thus, the research surrounding Arid5a recombinant protein is not only fundamental from a basic science perspective but also holds promise for translational applications in medicine.

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