| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | BAT5; NG26; PP199; D6S82E |
| Entrez GeneID | 7920 |
| WB Predicted band size | Calculated MW: 63 kDa; Observed MW: 55 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Rat |
| Immunogen | A synthetic peptide of human BAT5 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
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以下是关于BAT5抗体的虚构参考文献示例(仅供格式参考，非真实文献)：
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1. **文献名称**：*BAT5 Antibody Characterization in Autoimmune Disease Models*
**作者**：Smith J, et al.
**摘要**：本研究利用单克隆BAT5抗体分析其在系统性红斑狼疮(SLE)患者外周血细胞中的表达，发现BAT5蛋白水平与疾病活动度呈正相关，提示其可能作为免疫激活的生物标志物。
2. **文献名称**：*Role of BAT5 in Antigen Presentation: Insights from CRISPR Knockout Studies*
**作者**：Chen L, et al.
**摘要**：通过CRISPR技术敲除BAT5基因并利用特异性抗体检测，发现BAT5缺失会降低MHC-I类分子的稳定性，影响T细胞介导的抗肿瘤免疫反应。
3. **文献名称**：*Development of a High-Affinity BAT5 Antibody for Diagnostic Applications*
**作者**：Garcia R, et al.
**摘要**：报道了一种新型兔源多克隆BAT5抗体的开发，验证其在免疫组化中的特异性，成功应用于结直肠癌组织样本的肿瘤微环境分析。
4. **文献名称**：*BAT5 Antibody Reveals Altered Expression in Viral Infections*
**作者**：Watanabe K, et al.
**摘要**：使用BAT5抗体检测HIV感染者淋巴细胞，发现BAT5表达上调与病毒载量相关，可能参与宿主抗病毒应答调控。
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**备注**：以上文献为示例性内容，实际研究需通过PubMed、Web of Science等平台检索关键词(如“BAT5 antibody”、“HLA-BAT5 function”)获取真实数据。
The BAT5 antibody, often associated with B-cell research, targets specific antigens expressed during early B-cell development. Primarily used in immunophenotyping, it helps identify precursor B-cells in hematopoietic tissues, such as bone marrow. BAT5 is particularly recognized for detecting cytoplasmic immunoglobulin heavy chains (μ chains) in pre-B cells, a critical marker in B-cell maturation. This antibody is widely employed in diagnosing B-cell acute lymphoblastic leukemia (B-ALL), where malignant cells often retain early differentiation markers.
Developed as a tool for flow cytometry and immunohistochemistry, BAT5 aids in distinguishing normal B-cell precursors from leukemic blasts. Its reactivity is species-specific, typically optimized for human samples. Studies using BAT5 have contributed to understanding B-cell ontogeny and clonal malignancies, offering insights into minimal residual disease monitoring. Though less commonly referenced than markers like CD19 or CD20. BAT5 remains valuable in specialized hematopathology contexts, emphasizing its niche role in both research and clinical diagnostics.
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