关键信息
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基因名
Avpr1b
- 应用
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别名
AVPR V1bAVPR V3Antidiuretic hormone receptor 1bVasopressin V3 receptor
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种属
Rat
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P48974
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表达区间
343-425aa
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分子量
13 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
Avpr1b, or the arginine vasopressin receptor 1B, is a G protein-coupled receptor that plays a crucial role in the regulation of stress response, behavior, and various physiological processes. Research surrounding Avpr1b has gained momentum due to its involvement in neuroendocrine functions and its association with psychiatric disorders such as anxiety and depression. As a key player in the hypothalamic-pituitary-adrenal (HPA) axis, Avpr1b mediates the effects of vasopressin on the release of adrenocorticotropic hormone (ACTH), influencing stress-related behaviors and endocrine responses. Recombination of Avpr1b protein has become a focal point in studies aimed at elucidating its structure-function relationships, binding affinities, and signaling pathways. Moreover, understanding the molecular dynamics of Avpr1b through recombinant techniques could pave the way for novel therapeutic interventions targeting stress-related disorders. Investigating Avpr1b’s interactions within the central nervous system and its ligand-binding characteristics is essential for developing strategies to modulate its activity, potentially leading to better management options for anxiety and other stress-related conditions. Given its crucial physiological roles and implications in mental health, the study of recombinant Avpr1b protein is vital for advancing our comprehension of neurobiology and influencing the future of psychopharmacological therapies.
