关键信息
-
基因名
DSPP
- 应用
-
别名
DSP; DFNA39; DGI1; DPP; DTDP2; DMP3; Dentin phosphoprotein; Dentin phosphophoryn; Dentin sialoprotein
-
种属
Human
-
表达系统
E. coli
-
标签
N-His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9NZW4
-
表达区间
Gly82~Glu326
-
分子量
39kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
DSPP (dentin sialophosphoprotein) is a crucial protein involved in the formation and mineralization of dental tissues, particularly dentin. It is primarily expressed in odontoblasts, the cells responsible for dentin synthesis. DSPP plays a fundamental role in tooth development by serving as a structural protein that aids in the regulation of mineral deposition and the organization of the extracellular matrix in odontogenic tissues. Abnormalities in DSPP expression or mutations in its gene have been associated with various dental phenotypes, including dentinogenesis imperfecta and other developmental dental disorders. Researchers have been increasingly interested in DSPP recombinant protein for its potential applications in regenerative dentistry and tissue engineering, as it can provide insights into dentin formation and repair mechanisms. The generation of recombinant DSPP provides a valuable tool for studying its function and exploring its therapeutic potential in promoting tooth regeneration and enhancing dental restorations. By understanding the molecular mechanisms governed by DSPP and engineering this protein effectively, scientists aim to develop innovative treatment strategies to address dental pathologies and improve clinical outcomes in dentistry.
