关键信息
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基因名
LTBP2
- 应用
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别名
C14orf141; LTBP3
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q14767
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表达区间
Ser522~Thr814
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分子量
38kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
LTBP2 (Latent Transforming Growth Factor-beta Binding Protein 2) is a member of the LTBP family, which plays a crucial role in the regulation and activation of transforming growth factor-beta (TGF-β), a key cytokine involved in various biological processes, including tissue homeostasis, fibrosis, and immune response. The research into LTBP2 recombinant protein has gained momentum due to its potential implications in understanding pathological conditions such as fibrosis, cancer, and cardiovascular diseases, where TGF-β activity is often dysregulated. Investigating LTBP2 can provide insight into the extracellular matrix dynamics and TGF-β signaling pathways, shedding light on novel therapeutic targets for fibrotic diseases. Additionally, LTBP2's structural characteristics and its interactions with other extracellular matrix components contribute to the complexity of its functions, making it a subject of interest in developmental biology and regenerative medicine. The ability to produce LTBP2 as a recombinant protein offers a valuable tool for studying its biological functions in vitro and in vivo, facilitating studies that can unravel its role in health and disease. Understanding LTBP2's mechanisms may pave the way for innovative treatments and strategies to mitigate TGF-β-related pathologies, providing a clearer picture of the intricate balance between matrix remodeling and signaling in tissue repair and fibrosis.
