Rabbit Monoclonal TTC11 Antibody

The TTC11 antibody is a research tool designed to target the TTC11 (Tetratricopeptide Repeat Domain 11) protein, a member of the tetratricopeptide repeat (TPR) domain-containing family. TPR motifs are known for mediating protein-protein interactions, and TTC11 is hypothesized to play roles in cellular processes such as protein complex assembly, intracellular trafficking, or signal transduction. While the specific biological functions of TTC11 remain under investigation, it is expressed in various tissues, with studies suggesting potential involvement in ciliary function or chromatin remodeling. Dysregulation of TTC11 has been tentatively linked to certain cancers and developmental disorders, though mechanistic insights are limited. The TTC11 antibody is primarily utilized in experimental applications like Western blotting, immunofluorescence, and immunohistochemistry to detect TTC11 expression patterns, subcellular localization, and expression changes under pathological conditions. Its development aids in elucidating TTC11's interaction networks and pathological relevance. Commercial TTC11 antibodies are typically raised in hosts like rabbits or mice, with validation data confirming specificity through knockdown/knockout controls. Researchers employ this reagent to explore TTC11's role in disease models, often in conjunction with omics approaches to map its functional pathways.