| WB | 1/1000-1/2000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 1/50-1/200 | Human,Mouse,Rat |
| FCM | 1/20-1/100 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | FKHL5; foxf1; FREAC1; HFH 8;;FOXF1 |
| WB Predicted band size | 40 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human FOXF1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
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以下是关于FOXF1抗体的模拟参考文献示例(非真实文献，仅供格式参考)：
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1. **文献名称**: *FOXF1 Antibody Validation in Developmental Biology Studies*
**作者**: Zhang L, et al.
**摘要**: 本研究验证了FOXF1抗体在小鼠胚胎肺组织中的特异性，通过Western blot和免疫组化证实其可用于检测发育过程中FOXF1蛋白的动态表达，并揭示其在肺泡形成中的关键作用。
2. **文献名称**: *FOXF1 as a Biomarker in Gastrointestinal Stromal Tumors*
**作者**: Smith JR, et al.
**摘要**: 利用FOXF1抗体对临床肿瘤样本进行免疫组化分析，发现FOXF1高表达与胃肠道间质瘤的侵袭性相关，提示其作为潜在预后标志物的价值。
3. **文献名称**: *Technical Evaluation of Commercial FOXF1 Antibodies*
**作者**: Johnson M, et al.
**摘要**: 系统评估了5种市售FOXF1抗体的灵敏度和特异性，推荐克隆号HPA123456适用于染色质免疫沉淀(ChIP)研究，为功能基因组学提供可靠工具。
4. **文献名称**: *FOXF1 in Pulmonary Hypertension Pathogenesis*
**作者**: Wang Y, et al.
**摘要**: 通过FOXF1抗体检测肺动脉高压患者组织样本，发现FOXF1表达下调与血管重塑相关，为疾病机制研究提供分子层面依据。
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建议通过PubMed、Google Scholar或Web of Science搜索关键词“FOXF1 antibody”、“FOXF1 immunohistochemistry”等获取真实文献。
FOXF1 (Forkhead box F1) is a transcription factor belonging to the Forkhead family, characterized by a conserved DNA-binding "forkhead" domain. It plays critical roles in embryonic development, particularly in the formation and regulation of mesoderm-derived tissues, including the lung, gastrointestinal tract, and urogenital system. FOXF1 is essential for mesenchymal-epithelial interactions, influencing cell differentiation, proliferation, and organogenesis. Dysregulation of FOXF1 has been linked to developmental disorders, such as alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV), and certain cancers, including rhabdomyosarcoma and basal-like breast cancer.
FOXF1 antibodies are immunological tools used to detect and quantify FOXF1 protein expression in research and diagnostic settings. These antibodies enable the study of FOXF1's spatial and temporal expression patterns via techniques like immunohistochemistry (IHC), Western blotting, and immunofluorescence. They are vital for investigating FOXF1's functional mechanisms, including its role in signaling pathways (e.g., SHH, BMP) and interactions with regulatory elements. Commercially available FOXF1 antibodies vary in clonality, species reactivity, and validation standards, requiring careful selection based on experimental needs. Recent studies also explore FOXF1 as a potential biomarker for cancer prognosis and therapeutic targeting, underscoring its translational relevance. Proper validation, including knockout controls, is essential to ensure antibody specificity and reliability in diverse applications.
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