| WB | 1/1000-1/2000 | Human,Mouse,Rat |
| IF | 1/20-1/50 | Human,Mouse,Rat |
| IHC | IHC:1/100-1/200;IHF:1/50-1/200 | Human,Mouse,Rat |
| ICC | 1/50-1/200 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Cps1; CPSase 1; CPSase I; CPSASE1; MS738;;CPS1 |
| WB Predicted band size | Calculated MW: 165 kDa ; Observed MW: 150 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human CPS1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
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以下是关于CPS1抗体的3篇模拟文献示例(内容基于研究领域常见主题，建议通过学术数据库验证具体文献)：
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1. **文献名称**：*Carbamoyl Phosphate Synthetase 1 (CPS1) as a Mitochondrial Marker in Hepatocellular Carcinoma*
**作者**：Smith A, et al.
**摘要**：本研究利用CPS1抗体通过免疫组化技术分析肝癌组织，发现CPS1在肝细胞癌中特异性高表达，提示其可作为区分肝癌与其他转移性肿瘤的潜在生物标志物。
2. **文献名称**：*Role of CPS1 in Mitochondrial Urea Cycle Dysfunction*
**作者**：Chen L, et al.
**摘要**：通过Western blot和免疫荧光技术，作者使用CPS1抗体验证了尿素循环缺陷患者的线粒体中CPS1蛋白表达显著降低，表明其突变与新生儿高氨血症相关。
3. **文献名称**：*CPS1 Antibody Validation for Tissue-Specific Protein Quantification*
**作者**：Wang X, et al.
**摘要**：本文系统评估了多种CPS1抗体的特异性，确认其在肝组织和小肠组织中的选择性标记能力，并建立了基于ELISA的定量方法用于代谢疾病研究。
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**注意**：以上文献为模拟示例，实际引用时请通过PubMed、Google Scholar等平台检索真实文献(关键词如"CPS1 antibody"、"CPS1 biomarker"或"mitochondrial CPS1")。
The carbamoyl phosphate synthetase 1 (CPS1) antibody is a critical tool for studying CPS1. a mitochondrial enzyme central to the urea cycle. CPS1 catalyzes the first step of ammonia detoxification, converting bicarbonate and ammonia into carbamoyl phosphate. This rate-limiting reaction is vital for nitrogen metabolism, preventing hyperammonemia, a life-threatening condition. CPS1 is primarily expressed in the liver and, to a lesser extent, in intestinal epithelium.
CPS1 antibodies are widely used in research and diagnostics to assess protein expression, localization, and dysfunction. Mutations in the CPS1 gene cause CPS1 deficiency, a rare autosomal recessive disorder characterized by neonatal hyperammonemia. Antibody-based detection (e.g., Western blot, immunohistochemistry) helps diagnose this condition and study liver pathologies, including cirrhosis and hepatocellular carcinoma. Recent studies also implicate CPS1 in cancer metabolism, with altered expression linked to tumor progression and prognosis.
These antibodies are essential for elucidating CPS1's role in metabolic disorders, liver diseases, and cancer biology, bridging molecular insights with clinical applications.
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