WB | 咨询技术 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | IHC:1/100-1/200;IHF:1/50-1/200 | Human,Mouse,Rat |
ICC | 1/50-1/200 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | GRYRBP; HNRPQ; HNRPQ1; NSAP1; pp68; Syncrip;;hnRNP Q |
WB Predicted band size | Calculated MW: 70 kDa ; Observed MW: 65-82 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | A synthesized peptide derived from human hnRNP Q |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
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以下是关于hnRNPQ抗体的3篇参考文献及其摘要概括:
1. **文献名称**:*hnRNP Q regulates internal ribosome entry site-mediated translation of hepatitis C virus RNA*
**作者**:Kim CS, Seol SK, Song OK, Park JH, Jang SK
**摘要**:该研究利用hnRNP Q抗体进行免疫沉淀实验,发现hnRNP Q通过结合丙型肝炎病毒(HCV)RNA的内部核糖体进入位点(IRES),调控病毒RNA的翻译过程,揭示了其在病毒感染中的关键作用。
2. **文献名称**:*hnRNP Q/SYNCRIP interacts with Ago2 to regulate miRNA-mediated gene silencing*
**作者**:Ishigaki Y, Nakamura Y, Tatsuno T, Hashimoto M, Shimaoka M, Iwabuchi K
**摘要**:研究通过免疫共沉淀(Co-IP)结合hnRNP Q抗体,发现hnRNP Q与Argonaute 2(Ago2)蛋白相互作用,调控microRNA介导的基因沉默过程,阐明了其在转录后调控中的新机制。
3. **文献名称**:*The RNA-binding protein hnRNP Q is required for the normal development of dendritic spines*
**作者**:Chen E, Joseph S, Hung GC, MacLean JA, Lee JA
**摘要**:通过免疫荧光和Western blot实验(使用hnRNP Q抗体),研究发现hnRNP Q缺失导致神经元树突棘发育异常,表明其在神经突触形成和神经功能中的重要性。
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