关键信息
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基因名
TSPAN1
- 应用
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别名
Tetraspanin-1; Tspan-1; Tetraspan NET-1; Tetraspanin TM4-C
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种属
Human
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表达系统
HEK293
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O60635
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表达区间
Y110-N211
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蛋白长度
Partial
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分子量
13 kDa & 19-32 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
TSPAN1, or tetraspanin 1, is a member of the tetraspanin family, which is characterized by four transmembrane domains and is implicated in various cellular processes, including cell adhesion, migration, and signaling. Its role in cancer progression and metastasis has garnered significant interest, as TSPAN1 has been associated with the regulation of cancer cell behavior and the tumor microenvironment. Studies show that TSPAN1 enhances the invasive capabilities of cancer cells and is linked to poor prognosis in several malignancies. Its involvement in immune response modulation also suggests potential implications for therapeutic strategies targeting TSPAN1. Given its diverse functions and importance in disease, researchers are pursuing recombinant protein studies to elucidate TSPAN1's mechanisms of action, investigate its interactions with other proteins, and assess its potential as a biomarker or therapeutic target in cancer treatment. The production of TSPAN1 as a recombinant protein provides opportunities for in-depth structural and functional analyses, paving the way for novel interventions in oncology and immunotherapy.
